Irritability in child and adolescent psychopathology: An integrative review for ICD-11

Evans, Spencer C.; Burke, Jeffrey D.; Roberts, Michael C.; Fite, Paula J.; Lochman, John E.; Peña, Francisco R. de la; Reed, Geoffrey M.

doi:10.1016/j.cpr.2017.01.004

Cited by 148 publications

(133 citation statements)

References 147 publications

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“…This presentation is recognized to significantly increase the risk for subsequent depression and anxiety. The ICD‐11 conceptualization of this presentation as a form of oppositional defiant disorder is concordant with current evidence and diverges from the DSM‐5 approach of introducing a new disorder, disruptive mood dysregulation disorder.…”

Section: Summary Of Changes By Icd‐11 Disorder Groupingmentioning

confidence: 54%

Innovations and changes in the ICD‐11 classification of mental, behavioural and neurodevelopmental disorders

Reed¹,

First²,

Kogan³

et al. 2019

World Psychiatry

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612

343

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The development of the ICD-11 CDDG over the past decade, based on the principles of clinical utility and global applicability, has been the most broadly international, multilingual, multidisciplinary and participative revision process ever implemented for a classification of mental disorders. Innovations in the ICD-11 include the provision of consistent and systematically characterized information, the adoption of a lifespan approach, and culture-related guidance for each disorder. Dimensional approaches have been incorporated into the classification, particularly for personality disorders and primary psychotic disorders, in ways that are consistent with current evidence, are more compatible with recovery-based approaches, eliminate artificial comorbidity, and more effectively capture changes over time. Here we describe major changes to the structure of the ICD-11 classification of mental disorders as compared to the ICD-10, and the development of two new ICD-11 chapters relevant to mental health practice. We illustrate a set of new categories that have been added to the ICD-11 and present the rationale for their inclusion. Finally, we provide a description of the important changes that have been made in each ICD-11 disorder grouping. This information is intended to be useful for both clinicians and researchers in orienting themselves to the ICD-11 and in preparing for implementation in their own professional contexts.

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Section: Summary Of Changes By Icd‐11 Disorder Groupingmentioning

confidence: 54%

Innovations and changes in the ICD‐11 classification of mental, behavioural and neurodevelopmental disorders

Reed¹,

First²,

Kogan³

et al. 2019

World Psychiatry

Self Cite

612

343

View full text Add to dashboard Cite

show abstract

“…46 The next version of ICD will not add DMDD as a diagnosis, instead making a mood disturbance specifier for ODD. 97 Research needs to evaluate the relative effectiveness of psychosocial (eg, parent training; emotion regulation strategies) and pharmacologic interventions for DMDD. 61,98 Longitudinal data also raise interesting questions about the possibility of remission of DMDD and bipolar disorders, 55,99 a topic that warrants further study.…”

Section: | Clinical Characteristics Differential Diagnoses and Comentioning

confidence: 99%

The International Society for Bipolar Disorders Task Force report on pediatric bipolar disorder: Knowledge to date and directions for future research

et al. 2017

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Objectives Over the past two decades, there has been tremendous growth in research regarding bipolar disorder (BD) among children and adolescents (ie, pediatric BD [PBD]). The primary purpose of this article is to distill the extant literature, dispel myths or exaggerated assertions in the field, and disseminate clinically relevant findings. Methods An international group of experts completed a selective review of the literature, emphasizing areas of consensus, identifying limitations and gaps in the literature, and highlighting future directions to mitigate these gaps. Results Substantial, and increasingly international, research has accumulated regarding the phenomenology, differential diagnosis, course, treatment, and neurobiology of PBD. Prior division around the role of irritability and of screening tools in diagnosis has largely abated. Gold-standard pharmacologic trials inform treatment of manic/mixed episodes, whereas fewer data address bipolar depression and maintenance/continuation treatment. Adjunctive psychosocial treatment provides a forum for psychoeducation and targets primarily depressive symptoms. Numerous neurocognitive and neuroimaging studies, and increasing peripheral biomarker studies, largely converge with prior findings from adults with BD. Conclusions As data have accumulated and controversy has dissipated, the field has moved past existential questions about PBD toward defining and pursuing pressing clinical and scientific priorities that remain. The overall body of evidence supports the position that perceptions about marked international (US vs elsewhere) and developmental (pediatric vs adult) differences have been overstated, although additional research on these topics is warranted. Traction toward improved outcomes will be supported by continued emphasis on pathophysiology and novel therapeutics.

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“…Recent studies highlight an irritable dimension of ODD (Stringaris, Cohen, Pine, & Leibenluft, ; Rowe, Costello, Angold, Copeland, & Maughan, ; Krieger, Polanczyk, et al., ; Whelan, Stringaris, Maughan, & Barker, and Burke et al., ). The symptoms that best define this dimension include “often loses temper,” “often touchy or easily annoyed” and “often angry and resentful” (Evans et al., ). Irritability, when operationalized in the context of the irritable dimension of ODD or as a separate trait, has been found to predict future emotional disorders and depression (Krieger, Polanczyk, et al., ; Rowe et al., ; Stringaris & Goodman, ; Vidal‐Ribas, Brotman, Valdivieso, Leibenluft, & Stringaris, ; Whelan et al., ).…”

Section: Introductionmentioning

confidence: 99%

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability

Eyre

Hughes

Thapar

et al. 2019

Child Psychology Psychiatry

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Background Children with neurodevelopmental disorders are at increased risk of developing depression. Irritability predicts depression in the general population and is common in children with neurodevelopmental disorders. Thus, it is possible that irritability in children with neurodevelopmental disorders contributes to the link with later depression. This study aimed to (a) examine the association between childhood neurodevelopmental difficulties and adolescent depression and (b) test whether irritability explains this association. Methods Children with any neurodevelopmental difficulty at the age of 7–9 (n = 1,697) and a selected, comparison group without any neurodevelopmental difficulty (n = 3,177) were identified from a prospective, UK population‐based cohort, the Avon Longitudinal Study of Parents and Children. Neurodevelopmental difficulties were defined as a score in the bottom 5% of the sample on at least one measure of cognitive ability, communication, autism spectrum symptoms, attention‐deficit/hyperactivity symptoms, reading or motor coordination. The Development and Well‐Being Assessment measured parent‐reported child irritability at the age of 7, parent‐reported adolescent depression at the age of 10 and 13, and self‐reported depression at the age of 15. Depression measures were combined, deriving an outcome of major depressive disorder (MDD) in adolescence. Logistic regression examined the association between childhood neurodevelopmental difficulties and adolescent MDD, controlling for gender. Path analysis estimated the proportion of this association explained by irritability. Analyses were repeated for individual neurodevelopmental problems. Results Childhood neurodevelopmental difficulties were associated with adolescent MDD (OR = 2.11, 95% CI = 1.24, 3.60, p = .006). Childhood irritability statistically accounted for 42% of this association. On examining each neurodevelopmental difficulty separately, autistic, communication and ADHD problems were each associated with depression, with irritability explaining 29%–51% of these links. Conclusions Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group.

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Irritability in child and adolescent psychopathology: An integrative review for ICD-11

Cited by 148 publications

References 147 publications

Innovations and changes in the ICD‐11 classification of mental, behavioural and neurodevelopmental disorders

Innovations and changes in the ICD‐11 classification of mental, behavioural and neurodevelopmental disorders

The International Society for Bipolar Disorders Task Force report on pediatric bipolar disorder: Knowledge to date and directions for future research

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability

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