2017
DOI: 10.1097/01.naj.0000520253.57459.01
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Irritable Bowel Syndrome

Abstract: Irritable Bowel Syndrome (IBS) is a common, chronic gastrointestinal condition defined by disturbances in bowel habits and abdominal pain, in the absence of known organic pathology. IBS reduces patients’ quality of life, and exerts a substantial, negative impact on financial resources of patients and society at large. The diagnosis of IBS is made according to a symptom based classification system, the Rome Criteria, with updated guidelines, Rome IV, recently released. Physiological and psychological variables … Show more

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Cited by 54 publications
(67 citation statements)
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“…The prevalence rates of IBS are ranging from 7% to 21% in the general population [1]. IBS is branded by troubles in bowel habits and abdominal pain in the absence of recognized organic pathology [2]. IBS is widely accepted as a mysterious brain-gut complaint [3].…”
Section: Introductionmentioning
confidence: 99%
“…The prevalence rates of IBS are ranging from 7% to 21% in the general population [1]. IBS is branded by troubles in bowel habits and abdominal pain in the absence of recognized organic pathology [2]. IBS is widely accepted as a mysterious brain-gut complaint [3].…”
Section: Introductionmentioning
confidence: 99%
“…Irritable bowel syndrome is associated with hereditary factors, psychological factors and lifestyle habits. Psychological factors such as anxiety, and depression [7]. Lifestyle habits such as follows diet high in fat or irritating food, and smoking [6].…”
Section: Introductionmentioning
confidence: 99%
“…The development of the disease is closely associated with genetic background, psychosocial issues and inflammation of the host. Studies on the mechanism of IBS have focused on visceral hypersensitivity, abnormal GI motility, abnormalities in intestinal flora, low‐grade mucosal inflammation, altered pain perception by the central nervous system as well as humoral factors . However, the exact mechanism of IBS remains unclear and studies on its pathogenesis have focused on identifying the causes at the molecular level.…”
Section: Introductionmentioning
confidence: 99%