Irukandji Syndrome: A critique of current nursing management at The Townsville Hospital Emergency Department

Clarkson, Ryan S.G.

doi:10.1016/j.aenj.2010.04.002

Cited by 2 publications

(5 citation statements)

References 27 publications

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“…The article from Townsville Hospital mentions some success in patients who have received MgSO 4 and that medical treatment was consistent with the Irukandji Taskforce guidelines. However, it lacks specific details such as the severity of the syndrome, quantity of opiates received prior to receiving MgSO 4 , specific vital signs and pain score.…”

Section: Discussionmentioning

confidence: 93%

“…during 2 h) when pain recurred at 20 h . A clinical practice update from the Townsville Hospital ED lists in detail their current management plan for the care of patients with IS . The ED identified a total of 15 cases of IS from January 2006 and December 2008.…”

Section: Resultsmentioning

confidence: 99%

“…There were nine papers included in the review (Table 2). Of these, one article (randomised controlled trial [RCT]) does not support the use of MgSO 4 until further evidence supports its benefit, 20 another reports its failure based on anecdotal evidence, 27 while the remaining seven, 19,[22][23][24][25][26]28 which are case series, report some success in managing IS with MgSO 4 .…”

Section: Resultsmentioning

confidence: 99%

“…Unfortunately the study had to be terminated early as QAS and other healthcare providers adopted the use of MgSO 4 for IS in 2006 (during the trial). 24 The early termination of the trial because of external influences may be an explanation as to why the data concludes that there appears to be no difference between the two study groups. 31 However, the authors need to be commended on their efforts in recruiting suitable patients, when one has to consider the multiple agencies involved in the pre-hospital management of patients prior to arrival at the hospital.…”

Section: Discussionmentioning

confidence: 97%

“…There is also the high patient exclusion criteria, with only 39 of a possible 121 patients were recruited into the trial. Unfortunately the study had to be terminated early as QAS and other healthcare providers adopted the use of MgSO 4 for IS in 2006 (during the trial) . The early termination of the trial because of external influences may be an explanation as to why the data concludes that there appears to be no difference between the two study groups .…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Review article: Role of magnesium sulphate in the management of Irukandji syndrome: A systematic review

Rathbone

Franklin

Gibbs

et al. 2016

Emerg Medicine Australasia

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Signs of Irukandji syndrome (IS) suggest an underlying catecholamine storm with research demonstrating that Carukia barnesi venom causes a significant rise in adrenaline/noradrenaline serum levels. A systematic review was undertaken to ascertain the current evidence in treating IS with magnesium salts. A literature search was conducted using Scopus, Medline and ScienceDirect. Further articles were discarded via title description and/or abstract details. The remaining were read in full, and those identified as not having sufficient information regarding magnesium and patient outcomes were removed. Nine articles were identified. One article was a randomised controlled trial, which concluded that there appears to be no beneficial difference between those patients who received the magnesium sulphate (MgSO ) and those who received the placebo and recommended against the use of MgSO in IS. Of the remaining eight, one reported the failure of MgSO and the remaining seven were case series reporting varying success in its use. This systematic review found insufficient evidence to support any clear recommendation regarding the use of magnesium, but nor was there clear evidence to recommend against its use in IS. Two case series describe significant reduction in key symptoms and hypertension but are a non-randomised albeit prospective series with the limitations accompanying this. The reporting of recrudescence of symptoms with reduction of dose does suggest a dose-response relationship. The evidence for the use of MgSO is at best anecdotal, and further research is required to either confirm its benefit or confirm the randomised controlled trial.

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Section: Discussionmentioning

confidence: 93%

Section: Resultsmentioning

confidence: 99%