Is a Retroaortic Vein a Risk Factor in Laparoscopic Living Donor Nephrectomy?

Mang, Josef; Hennig, L; Biernath, Nadine; Liefeldt, Lutz; Bichmann, Anna; Ralla, Bernhard; Maxeiner, Andreas; Peters, Robert W.; Cash, Hannes; Budde, Klemens; Friedersdorff, Frank

doi:10.1159/000507642

Cited by 5 publications

(2 citation statements)

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“…Patient preparation and surgical technique (laparoscopic donor nephrectomy and renal transplantation) were described in a previous study. 12 …”

Section: Methodsmentioning

confidence: 99%

Focal Segmental Glomerulosclerosis and Recurrence in Living Donor Recipients

Mang¹,

Hennig²,

Liefeldt³

et al. 2021

RRU

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Focal segmental glomerulosclerosis (FSGS) is a common cause for end-stage renal disease that can recur in the graft after kidney transplantation. The incidence of FSGS recurrence is reported in up to 47% of patients, predisposing those to possible poorer transplantation outcomes. Hence, we examined the incidence of FSGS recurrence and the effect on graft outcome in our patient cohort of living donor kidney transplantations (LDKT). Patients and Methods: We analyzed 194 adult patients who received a LDKT between 2011 and 2017 of which 22 (11%) had FSGS as underlying disease. Demographic data and clinical outcomes, especially regarding recurrence of FSGS, were evaluated. Results: FSGS recurrence was identified in three (14%) patients within three months after transplantation, of whom two patients (9%) lost their graft. There was no significant difference in graft survival comparing FSGS to other reasons for end-stage renal disease. Conclusion: Incidence of FSGS recurrence in the present patient cohort was within the range reported in the literature and comparatively low. Our data support LDKT as a treatment option in patients with end-stage renal disease due to FSGS.

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“…Patient preparation and surgical technique (laparoscopic donor nephrectomy and renal transplantation) were described in a previous study. 12 …”

Section: Methodsmentioning

confidence: 99%

Focal Segmental Glomerulosclerosis and Recurrence in Living Donor Recipients

Mang¹,

Hennig²,

Liefeldt³

et al. 2021

RRU

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“…Anatomic workup prior living donor transplantation (LDKT) is a crucial part in the selection of the donor nephrectomy side to avoid surgical complications in donor and recipient. Kidneys and their vascular supply is predisposed to congenital anomalies such as accessory renal arteries (ARAs) [ 1 ]. ARAs are present in 20 to 30% of the population and can occur bilaterally in nearly 10% [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Retrospective analysis of the perioperative outcome in living donor kidney transplantation with multiple renal arteries: does accessory vessel ligation affect the outcome?

Schmidt,

Peters,

Mang

et al. 2024

World J Urol

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Purpose Accurate surgical reconstruction of arterial vascular supply is a crucial part of living kidney transplantation (LDKT). The presence of multiple renal arteries (MRA) in grafts can be challenging. In the present study, we investigated the impact of ligation versus anastomosis of small accessory graft arteries on the perioperative outcome. Methods Clinical and radiological outcomes of 51 patients with MRA out of a total of 308 patients who underwent LDKT with MRA between 2011 and 2020 were stratified in two groups and analyzed. In group 1 (20 patients), ligation of accessory arteries (ARAs) and group 2 (31 patients) anastomosis of ARAs was performed. Results Significant differences were observed in the anastomosis-, surgery-, and warm ischemia time (WIT) in favor of group 1. Students t-test showed comparable serum creatinine levels of 2.33 (± 1.75) to 1.68 (± 0.83) mg/dL in group 1 and 2.63 (± 2.47) to 1.50 (± 0.41) mg/dL in group 2, were seen from 1 week to 1 year after transplant. No increased rates of Delayed graft function (DGF), primary transplant dysfunction and transplant rejection were seen, but graft loss and revision rates were slightly higher when the ARAs were ligated. Analysis of Doppler sonography revealed that segmental perfusion deficits tend to regenerate during the clinical course. Conclusion Ligation of smaller accessory renal arteries may not affect the outcome of living kidney transplantation, except for a minor increase in the reoperation rate. Segmental perfusion deficits of the graft seem to regenerate in most cases as seen in Doppler sonography.

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