Is all chronic kidney disease created equal?

Abstract

CKD includes a diverse group of individuals with reduced GFR from a variety of causes. Classification of CKD according to GFR, albuminuria, and cause, may improve the management of patients with reduced GFR, as some causes (e.g., nephrectomy and aging) appear to be associated with a relatively low risk of progression.

End-Stage Renal Disease After Renal Surgery in Patients with Normal Preoperative Kidney Function: Balancing Surgical Strategy and Individual Disorders at Baseline

“…An even greater benefit is possible with the novel surgical techniques of no clamp or selective clamping, which were recently reported [1]. As already verified by others [8], baseline medical conditions that may produce renal functional impairment remain the key and most informative causes of renal failure, regardless of all surgical efforts to preserve nephrons [9]. However, our findings also corroborate the beneficial effect of NSS for the consequences of a baseline medical condition favoring chronic kidney disease [9].…”

Predictors of new‐onset chronic kidney disease in patients managed surgically for T1a renal cell carcinoma: An Australian population‐based analysis

“…The primary outcome of our study was new‐onset CKD (postoperative eGFR <60 mL/min per 1.73 m 2 ). As there are concerns about the clinical significance of using such a broad definition of CKD following kidney surgery, we also considered postoperative eGFR <45 mL/min per 1.73 m 2 (new‐onset moderate‐severe CKD) as a secondary outcome. Both groups were compared with patients who had a postoperative eGFR ≥60 mL/min per 1.73 m 2 .…”

Prospective assessment of urinary neutrophil gelatinase‐associated lipoprotein in living kidney donors: toward understanding differences between chronic kidney diseases of surgical and medical origin

“…Lane et al verified that survival is better for sCKD than for mCKD, particularly if the postoperative GFR is <45 mL/min/1.73 m 2 . Because the causes of CKD are diverse and their prognoses differ, accurate aetiological classification is required, instead of simply relying on eGFR assessments . However, limitations existed in previous studies, as they all targeted patients, such as individuals with kidney tumours.…”