Is Anopheles gambiae (sensu stricto), the principal malaria vector in Africa prone to resistance development against new insecticides? Outcomes from laboratory exposure of An. gambiae (s.s.) to sub-lethal concentrations of chlorfenapyr and clothianidin

Azizi, Salum; Mbewe, Njelembo J.; Mo, Hosiana; Edward, Felista; Sumari, Godwin; Mwacha, Silvia; Msapalla, Agness; Mawa, Benson; Mosha, Franklin; Matowo, Johnson

doi:10.1016/j.crpvbd.2024.100172

Current Research in Parasitology & Vector-Borne Diseases

2024

DOI: 10.1016/j.crpvbd.2024.100172

|View full text |Cite

Is Anopheles gambiae (sensu stricto), the principal malaria vector in Africa prone to resistance development against new insecticides? Outcomes from laboratory exposure of An. gambiae (s.s.) to sub-lethal concentrations of chlorfenapyr and clothianidin

Salum Azizi,

Njelembo J. Mbewe,

Hosiana Mo

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Insecticide tolerance of the malaria vector Anopheles gambiae following larval exposure to microplastics and insecticide

Shilla,

Matiya,

Nyamandito

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Microplastic (MP) pollution poses a global threat to urban and rural environments and can have negative effects on a range of organisms. Mosquito larvae often breed in water contaminated with MPs, and given their important role as disease vectors, understanding the effects of larval exposure to MPs is critical for understanding the potential impact on their life history traits and subsequent methods for their control. Here, we have exposed first instar larvae of Anopheles gambiae s.s. to environmentally realistic concentrations of PET microplastics (1.0–7.5 μm) and a sub-lethal dose of insecticide mixed with microplastics, and quantified survival, development, and susceptibility of larvae over six generations. Adult mosquitoes from larvae exposed to these treatments were subsequently tested for insecticide resistance. Exposure to MPs decreased larval survival rates compared to the control; however, over six generations of exposure, survival rates significantly increased. Similarly, there was a higher survival rate of those larvae exposed to MPs mixed with insecticide compared to those exposed to just the insecticide, and survival increased further over the six generations. For the adult mosquito susceptibility tests, knockdown times (KDTs) indicated some level of insecticide tolerance when larvae had been previously exposed to MPs and insecticides. This is the first study demonstrating the selection of insecticide tolerance in adult mosquitoes after consecutive generations of larval exposures to varying concentrations of MPs. Therefore, field-scale studies are now urgently required to quantify whether larval insecticides are less effective at controlling mosquitoes in breeding sites commonly polluted with MPs.

show abstract

Insecticide tolerance of the malaria vector Anopheles gambiae following larval exposure to microplastics and insecticide

Shilla,

Matiya,

Nyamandito

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Is Anopheles gambiae (sensu stricto), the principal malaria vector in Africa prone to resistance development against new insecticides? Outcomes from laboratory exposure of An. gambiae (s.s.) to sub-lethal concentrations of chlorfenapyr and clothianidin

Cited by 1 publication

References 67 publications

Insecticide tolerance of the malaria vector Anopheles gambiae following larval exposure to microplastics and insecticide

Insecticide tolerance of the malaria vector Anopheles gambiae following larval exposure to microplastics and insecticide

Contact Info

Product

Resources

About