Is Antibiotic Prophylaxis for Percutaneous Radiofrequency Ablation (RFA) of Primary Liver Tumors Necessary? Results From a Single-Center Experience

Bhatia, Shivank; Spector, Seth A.; Echenique, Ana; Froud, Tatiana; Suthar, Rekha; Lawson, Ivy; Dalal, Ravi; Dinh, Vy; Yrizarry, Jose M.; Narayanan, Govindarajan

doi:10.1007/s00270-014-1020-0

Cited by 19 publications

(8 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At our institution, we do not administer empirical antibiotic before hepatic tumor ablation because we argue that it may not be necessary given both the sterile nature of the procedure and the lack of solid evidence supporting the use. However, recent study shows it may be feasible in high risk patients such as elderly, those with diabetes, bilioenteric anastomosis (BEA) or other biliary issues and tumor positioned near central bile duct [11] . Retrospectively, taking into account of our patient’s advanced age and past history of gastrectomy, we wonder whether such complication can be avoided should prophylaxis was given prior to the procedure.…”

Section: Discussionmentioning

confidence: 99%

Microwave ablation of liver metastasis complicated by Clostridium perfringens gas-forming pyogenic liver abscess (GPLA) in a patient with past gastrectomy

Kyang

Traiki

Alzahrani

et al. 2016

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

HighlightsGPLA is one rare complication of liver microwave ablation.It can be diagnosed with CT scan which shows gas-containing infective focus.Patients with gastrectomy may have an increased risk of such infection due to gut flora change.To date, data on effectiveness of empirical antibiotic is not convincing.Close monitoring following ablation should be prioritised to allow timely intervention and prevent escalation of infection.

show abstract

Section: Discussionmentioning

confidence: 99%

Microwave ablation of liver metastasis complicated by Clostridium perfringens gas-forming pyogenic liver abscess (GPLA) in a patient with past gastrectomy

Kyang

Traiki

Alzahrani

et al. 2016

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

show abstract

“…One patient with a hepaticojejunostomy after a pancreaticoduodenectomy presented with an abscess in the ablation zone and was treated with antibiotics. This population has been identified as at higher risk for post-ablation abscesses 22,23 . Following this, we implemented a prophylactic antibiotic regimen in all patients undergoing SMWA.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous stereotactic image-guided microwave ablation for malignant liver lesions

Perrodin

Lachenmayer

Maurer

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Thermal ablation has proven beneficial for hepatocellular carcinoma and possibly for colorectal liver metastases, but data is lacking for other liver metastases. Computer-assisted navigation can increase ablation efficacy and broaden its indications. We present our experience with percutaneous stereotactic image-guided microwave ablation (SMWA) for non-colorectal liver metastases (NCRLM), in form of a retrospective study including all SMWA for NCRLM from 2015 to 2017. Indication for SMWA was determined at a multidisciplinary tumorboard. End-points include recurrence, overall and liver-specific disease progression and complications. Twenty-three patients underwent 25 interventions for 40 lesions, including 17 neuroendocrine tumor, nine breast cancer, four sarcoma, two non-small cell lung cancer, three duodenal adenocarcinoma, one esophageal adenocarcinoma, one pancreatic adenocarcinoma, one ampullary carcinoma, one prostate carcinoma, and one renal cell carcinoma metastases. Median follow-up was 15 months (2–32). Incomplete ablation rate was 2.5% (1/40), local recurrence rate 10% (4/40). Three patients (12%) had minor complications. Overall disease progression was 73.9% (17/23), median disease-free survival 7 months (0–26) and overall survival 18 months (2–39). SIMWA is feasible, safe and minimally invasive for NCRLM in selected patients. While it might offer an alternative to resection or palliative strategies, the oncological benefit needs to be evaluated in a larger patient cohort.

show abstract

“…In another study by Bhatia et al, 123 RFA procedures were performed in 83 patients. 51 None of the patients had the risk factors like prior bilioenteric anastomoses, biliary tract abnormalities, or uncontrolled diabetes mellitus. No prophylactic antibiotics were given for 121 sessions.…”

Section: Evidence and Rationalementioning

confidence: 99%

Indian Society of Vascular and Interventional Radiology Expert Consensus Statements for Ablation in Hepatocellular Carcinoma: Part I

Gupta

Kalra

Keshava

et al. 2020

Journal of Clinical Interventional Radiology ISVIR

View full text Add to dashboard Cite

Locoregional therapies play an important role in the management of hepatocellular carcinoma (HCC). Percutaneous ablation is one of the most commonly employed nonsurgical methods for treating very early and early HCC. For small HCCs, ablation is potentially curative and competes with surgical resection. The widespread availability and the spectrum of ablative techniques mandate uniform approach among interventional radiologists. Thus, it is desirable to have a consensus regarding various aspects of liver ablation. This article represents a consensus document of the experts from the Indian Society of Vascular and Interventional Radiology involved in the care of patients with HCC. The statements are presented in two parts.

show abstract

Is Antibiotic Prophylaxis for Percutaneous Radiofrequency Ablation (RFA) of Primary Liver Tumors Necessary? Results From a Single-Center Experience

Cited by 19 publications

References 23 publications

Microwave ablation of liver metastasis complicated by Clostridium perfringens gas-forming pyogenic liver abscess (GPLA) in a patient with past gastrectomy

Microwave ablation of liver metastasis complicated by Clostridium perfringens gas-forming pyogenic liver abscess (GPLA) in a patient with past gastrectomy

Percutaneous stereotactic image-guided microwave ablation for malignant liver lesions

Indian Society of Vascular and Interventional Radiology Expert Consensus Statements for Ablation in Hepatocellular Carcinoma: Part I

Contact Info

Product

Resources

About