Is atomic layer deposition of silver possible on N95 masks?

Astaneh, Sarah Hashemi; Bhatia, Harshdeep; Nagay, B; Barão, Valentim Adelino Ricardo; Jursich, Gregory; Sukotjo, Cortino; Takoudis, Christos G.

doi:10.1016/j.apsusc.2022.153195

Cited by 9 publications

(5 citation statements)

References 52 publications

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“…For S. aureus, absorbance was adjusted at an OD of 0.3 at a fixed wavelength of 550 nm and added in BHI medium (1:10 v/v) (≈1.7 × 10 7 CFU/mL) . For C.…”

Section: Methodsmentioning

confidence: 99%

Effect of Processing Methods of Human Saliva on the Proteomic Profile and Protein-Mediated Biological Processes

et al. 2023

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The use of saliva as a protein source prior to microbiological and biological assays requires previous processing. However, the effect of these processing methods on the proteomic profile of saliva has not been tested. Stimulated human saliva was collected from eight healthy volunteers. Non-processed saliva was compared with 0.22 μm filtered, 0.45 μm filtered, and pasteurized saliva, by liquid chromatography−mass spectrometry. Data are available via ProteomeXchange with identifier PXD039248. The effect of processed saliva on microbial adhesion was tested using bacterial and fungus species and in biological cell behavior using HaCaT immortalized human keratinocytes. Two hundred and seventy-eight proteins were identified in non-processed saliva, of which 54 proteins (≈19%) were exclusive. Saliva processing reduced identified proteins to 222 (≈80%) for the 0.22 μm group, 219 (≈79%) for the 0.45 μm group, and 201 (≈72%) for the pasteurized saliva, compared to non-processed saliva. The proteomic profile showed similar molecular functions and biological processes. The different saliva processing methods did not alter microbial adhesion (ANOVA, p > 0.05). Interestingly, pasteurized saliva reduced keratinocyte cell viability. Saliva processing methods tested reduced the proteomic profile diversity of saliva but maintained similar molecular functions and biological processes, not interfering with microbial adhesion and cell viability, except for pasteurization, which reduced cell viability.

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“…For S. aureus, absorbance was adjusted at an OD of 0.3 at a fixed wavelength of 550 nm and added in BHI medium (1:10 v/v) (≈1.7 × 10 7 CFU/mL) . For C.…”

Section: Methodsmentioning

confidence: 99%

Effect of Processing Methods of Human Saliva on the Proteomic Profile and Protein-Mediated Biological Processes

et al. 2023

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“…Although the results [123] show an improvement in the suppression of biofilm formation with smaller silver particles, the effect of particle size on its antibacterial activity and cytotoxicity/biocompatibility remains controversial. The duration of the silver effect and the onset of action also remain open, as the results showed that 2 h was not sufficient for effective bacteria/Ag contact, whereas after a longer time (24 h) effective contact occurred, resulting in a reduction in biofilm formation [123].…”

Section: Nm S Aureusmentioning

confidence: 99%

“…In terms of practical applications, the work [123], in which Ag nanoislands were obtained on the surface of N95 medical masks at relatively low temperatures (90 and 120 • C) via ALD is of great importance. Such coatings can be very effective in increasing the service life and reliability of personal protective equipment (PPE), as such particles prevent microbial contamination and accumulation in the membranes and fibers of PPE.…”

Section: Nm S Aureusmentioning

confidence: 99%

“…Therefore, it is necessary to carry out studies on the selection of an optimal reducing agent. In [123], borane dimethylamine complex ((CH 3 ) 2 NH*BH 3 ) was tested as a co-reagent. The results indeed showed silver growth in the inner layers of the fibrous structure of the N95 filter media.…”

Section: Nm S Aureusmentioning

confidence: 99%

“…However, technical advances in recent years suggest that the impact of these negative factors can be reduced. In particular, we should note the development of technically simpler technologies such as atmospheric pressure ALD [142,143] and faster roll-to-roll ALD, spatial ALD [19], as well as the emergence of techniques that avoid the use of plasma to produce silver [123,144]. We believe that the advancement of these technologies could greatly augment the likelihood of extensive application of ALD in the manufacturing of antibacterial-coated materials within the industry.…”

Section: Advantages Disadvantages and Perspectives Of Aldmentioning

confidence: 99%

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Atomic Layer Deposition of Antibacterial Nanocoatings: A Review

Nazarov,

Kozlova,

Rogacheva

et al. 2023

Antibiotics

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In recent years, antibacterial coatings have become an important approach in the global fight against bacterial pathogens. Developments in materials science, chemistry, and biochemistry have led to a plethora of materials and chemical compounds that have the potential to create antibacterial coatings. However, insufficient attention has been paid to the analysis of the techniques and technologies used to apply these coatings. Among the various inorganic coating techniques, atomic layer deposition (ALD) is worthy of note. It enables the successful synthesis of high-purity inorganic nanocoatings on surfaces of complex shape and topography, while also providing precise control over their thickness and composition. ALD has various industrial applications, but its practical application in medicine is still limited. In recent years, a considerable number of papers have been published on the proposed use of thin films and coatings produced via ALD in medicine, notably those with antibacterial properties. The aim of this paper is to carefully evaluate and analyze the relevant literature on this topic. Simple oxide coatings, including TiO2, ZnO, Fe2O3, MgO, and ZrO2, were examined, as well as coatings containing metal nanoparticles such as Ag, Cu, Pt, and Au, and mixed systems such as TiO2-ZnO, TiO2-ZrO2, ZnO-Al2O3, TiO2-Ag, and ZnO-Ag. Through comparative analysis, we have been able to draw conclusions on the effectiveness of various antibacterial coatings of different compositions, including key characteristics such as thickness, morphology, and crystal structure. The use of ALD in the development of antibacterial coatings for various applications was analyzed. Furthermore, assumptions were made about the most promising areas of development. The final section provides a comparison of different coatings, as well as the advantages, disadvantages, and prospects of using ALD for the industrial production of antibacterial coatings.

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