Is Atrial Electromechanical Coupling Delayed in Patients with Secundum Atrial Septal Defect?

Oflaz, Mehmet Burhan; Karapınar, Hekim; Küçükdurmaz, Zekeriya; Güven, Ahmet Sami; Gümrükçüoğlu, Hasan Ali; Sarıkaya, Savaş; Yılmaz, Ahmet

doi:10.1111/echo.12221

Cited by 3 publications

(6 citation statements)

References 25 publications

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“…Groups were similar for age and gender (52 AE 12.3 vs. 49.9 AE 6 years, P > 0.05; 25 [53%] vs. 23 [56%] female, P > 0.05). Furthermore, there was no significant difference between the groups with respect to SBP and DBP (P > 0.05), but heart rate was higher in the ESRF group (75.4 AE 10 vs. 66.7 AE 7.8, P < 0.001).…”

Section: Resultsmentioning

confidence: 90%

“…Predicting AF by atrial EMCTs is a more recent method which is noninvasive and correlated with electrophysiological measured conduction times. 25 Left atrial emptying is easy in patients with atrial septal defect because of reduced afterload when compared with the patients with atrial septal aneurism or healthy subjects. 7,[9][10][11] Electromechanical coupling time is a function of conduction time and hemodynamic of the atria.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Atrial Electromechanical Coupling Times in Hemodialysis Patients

et al. 2013

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Section: Resultsmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Evaluation of Atrial Electromechanical Coupling Times in Hemodialysis Patients

et al. 2013

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“…In the study of Oflaz et al, 7 the patients with ASD (24.9 AE 14.3 years vs. 40.7 AE 13.81 years) were younger than those in the study of Erturk et al 6 It is well documented in the natural history studies of ASDs that patients frequently remain asymptomatic until adulthood. The reasons for such differences are not clear.…”

Section: See Articles On Pages 699 and 706mentioning

confidence: 88%

“…However, the sample sizes are different: 72 versus 35 in ASD groups and 35 versus 22 in control groups, which may be a factor, at least partially accounting for this difference. In the study of Oflaz et al, 7 the patients with ASD (24.9 AE 14.3 years vs. 40.7 AE 13.81 years) were younger than those in the study of Erturk et al 6 It is well documented in the natural history studies of ASDs that patients frequently remain asymptomatic until adulthood. The majority develop symptoms beyond the fourth decade of life including reduced functional capacity, exertional shortness of breath, palpitations (supraventricular tachyarrhythmia), and less frequently pulmonary infections and right heart failure.…”

Section: See Articles On Pages 699 and 706mentioning

confidence: 88%

“…The authors conclude that left atrial reservoir and contractile pump functions are decreased and the left intraatrial, right intra-atrial and inter-atrial electromechanical delays are increased in the patients with ASD. Oflaz et al 7 also evaluated AEMD in 35 patients with secundum ASDs and compared them with those of 22 age-matched control subjects. They found that the PA intervals and AE-MDs were marginally longer in the ASD group, although these values did not reach statistical significance.…”

Section: See Articles On Pages 699 and 706mentioning

confidence: 99%

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Atrial Electromechanical Delay Measured by Tissue Doppler Imaging in Patients with Secundum Atrial Septal Defects

Biliciler-Denktas

Rao

2013

Echocardiography

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SEE ARTICLES ON PAGES 699 AND 706Atrial septal defects (ASDs) cause left-to-right shunt because the pressure in the left atrium is usually higher than the right atrial pressure. Left-to-right shunting across the ASD produces dilatation and hypertrophy of the right atrium and right ventricle. The resulting increased pulmonary venous return causes left atrial dilatation. Enlarged atria may increase conduction time of the impulse originating in the sinus node as well as result in nonhomogeneous spread of the electrical impulse. These abnormalities may in part be responsible for tachyarrhythmias seen in patients with ASD. Atrial electromechanical delay (AEMD) may characterize these abnormalities and has been measured in the past during invasive electrophysiologic studies. 1 Tissue Doppler imaging (TDI) uses Doppler echocardiography to image the motion of the tissue. Doppler echocardiography measures blood flow velocity while TDI measures myocardial tissue velocity, which has higher amplitude but lower velocity signals. 2 Primary measurements include the systolic (S), early diastolic (Ea or E′), and late diastolic (Aa or A′) velocities. The AEMD mentioned in the preceding paragraph can also be measured noninvasively using TDI. The time interval between the onset of Pwave on the electrocardiogram to the A-wave of the simultaneously recorded TDI may be termed PA interval and can be recorded from lateral and septal mitral annuli and lateral tricuspid (right ventricle) annulus locations and right intra-AEMD, left intra-AEMD and inter-AEMD may be calculated. 3-5 There appears to be interest in assessing the atrial function using AEMD in patients with different disease states including mitral stenosis, familial Mediterranean fever, rheumatoid arthritis, atrial septal aneurysms, atrial fibrillation, scleroderma, ankylosing spondylitis, and type 1 diabetes. [3][4][5] There is limited experience in use of this technique in patients with ASDs.In a recent publication 6 as well as in the current issue of the Journal, 7 AEMD in patients with atrial septal defects has been investigated. Erturk et al. 6 evaluated AEMD and left atrial mechanical function in 72 patients with secundum ASD and compared them with those of 35 gender and age-matched control subjects. They found that left atrial active and total emptying fractions and conduit volumes were lower and total emptying volume was higher in the patients with ASD compared to the control group while passive emptying volume and fraction and active emptying volumes were not different significantly between the groups. The left intra-atrial, right intra-atrial and inter-atrial EMDs were also significantly longer in the ASD group. The authors conclude that left atrial reservoir and contractile pump functions are decreased and the left intraatrial, right intra-atrial and inter-atrial electromechanical delays are increased in the patients with ASD. Oflaz et al. 7 also evaluated AEMD in 35 patients with secundum ASDs and compared them with those of 22 age-matched control subjects. They foun...

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Effects of percutaneous closure of atrial septal defect on left atrial mechanical and conduction functions

Aslan

Ertürk

Turen

et al. 2014

European Heart Journal - Cardiovascular Imaging

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Is Atrial Electromechanical Coupling Delayed in Patients with Secundum Atrial Septal Defect?

Abstract: Both intra- and inter-AEMCT were not increased in patients with ASD than control subjects. In addition, we found no association between the ASD diameter and indices of AEMCT in patients with ASD.

Cited by 3 publications

References 25 publications

Evaluation of Atrial Electromechanical Coupling Times in Hemodialysis Patients

Evaluation of Atrial Electromechanical Coupling Times in Hemodialysis Patients

Atrial Electromechanical Delay Measured by Tissue Doppler Imaging in Patients with Secundum Atrial Septal Defects

Effects of percutaneous closure of atrial septal defect on left atrial mechanical and conduction functions

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