Is bipolar disorder a risk factor for HIV infection?

Ribeiro, Carolina Medeiros da Frota; Gurgel, Wagner de Sousa; Luna, João Rafael Gomes de; Matos, Karla Julianne Negreiros de; Souza, Francis Ribeiro de

doi:10.1016/j.jad.2012.08.039

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…BD has a significant prevalence among HIV/AIDS sufferers -about 2.6% [31]. BD patients are more prone to risky sexual behaviour than others, and among sero-positive individuals1.2% have been recognised as suffering from secondary mania indicative of AIDS progression [32].…”

Section: Bipolar Disordermentioning

confidence: 99%

Psychiatric Challenges of HIV/AIDS and the Added Problems of Aging with Seropositive Status

Pandarakalam

2018

GGS

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Serious emotional reactions consequent to sero-positive diagnosis 2 Neurocognitive changes as side effects of HIV infection 3 Opportunistic neurological and systemic infections and their treatments leading to neuropsychiatric complications 4 Psychiatric side effects of highly active anti-retroviral therapy 5 Vulnarability posing risks to patients suffering from severe mental illness 6 Direct and indirect links of substance abuse

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Section: Bipolar Disordermentioning

confidence: 99%

Psychiatric Challenges of HIV/AIDS and the Added Problems of Aging with Seropositive Status

Pandarakalam

2018

GGS

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“…At the introduction of highly active antiretroviral therapy (ART) (1996), estimates of 12-month prevalence of MHDs among PWH in the United States found nearly half of PWH screened positive for one or more of: major depression, dysthymia, generalized anxiety disorder, or panic attacks [4]. Studies have reported the prevalence of major depression, anxiety, bipolar disorder (BD), and schizophrenia are more common among PWH compared to the general population [5][6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

The prevalence of mental health disorders in people with HIV and the effects on the HIV care continuum

Lang

Hogan

Zhu

et al. 2022

Aids

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Objective:To describe the prevalence of diagnosed depression, anxiety, bipolar disorder, and schizophrenia in people with HIV (PWH) and the differences in HIV care continuum outcomes in those with and without mental health disorders (MHDs).Design:Observational study of participants in the North American AIDS Cohort Collaboration on Research and Design.Methods:PWH (≥18 years) contributed data on prevalent schizophrenia, anxiety, depressive, and bipolar disorders from 2008 to 2018 based on International Classification of Diseases code mapping. Mental health (MH) multimorbidity was defined as having two or more MHD. Log binomial models with generalized estimating equations estimated adjusted prevalence ratios (aPR) and 95% confidence intervals for retention in care (≥1 visit/year) and viral suppression (HIV RNA ≤200 copies/ml) by presence vs. absence of each MHD between 2016 and 2018.Results:Among 122 896 PWH, 67 643 (55.1%) were diagnosed with one or more MHD: 39% with depressive disorders, 28% with anxiety disorders, 10% with bipolar disorder, and 5% with schizophrenia. The prevalence of depressive and anxiety disorders increased between 2008 and 2018, whereas bipolar disorder and schizophrenia remained stable. MH multimorbidity affected 24% of PWH. From 2016 to 2018 (N = 64 684), retention in care was marginally lower among PWH with depression or anxiety, however those with MH multimorbidity were more likely to be retained in care. PWH with bipolar disorder had marginally lower prevalence of viral suppression (aPR = 0.98 [0.98–0.99]) as did PWH with MH multimorbidity (aPR = 0.99 [0.99–1.00]) compared with PWH without MHD.Conclusion:The prevalence of MHD among PWH was high, including MH multimorbidity. Although retention and viral suppression were similar to people without MHD, viral suppression was lower in those with bipolar disorder and MH multimorbidity.

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“…At the introduction of highly active antiretroviral therapy (ART) (in 1996), the first national estimates of 12-month prevalence of MHD among PWH in the US reported that nearly half of PWH screened positive for 1 of the following: major depression, dysthymia, generalized anxiety disorder, or panic attacks [4] . More recent studies have reported the prevalence of major depression, anxiety, bipolar disorder (BD), and schizophrenia are all more common among PWH compared to the general population [5][6][7][8][9][10][11][12][13] .…”

Section: Introductionmentioning

confidence: 99%

The Prevalence of Mental Health Disorders in people with HIV and the effects on the HIV Care Continuum

Lang

Hogan

Zhu

et al. 2022

Preprint

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ObjectiveTo describe the prevalence of diagnosed depression, anxiety, bipolar disorder, and schizophrenia in people with HIV (PWH) and the differences in HIV care continuum outcomes in those with and without mental health disorders (MHD).DesignObservational study of participants in the NA-ACCORD.MethodsPWH (≥18 years) contributed data on prevalent schizophrenia, anxiety, depressive, and bipolar disorders from 2008-2018 based on ICD code mapping. MH multimorbidity was defined as having ≥ 2 MHD. Log binomial models with generalized estimating equations estimated adjusted prevalence ratios (aPR) and 95% confidence intervals for retention in care (≥ 1 visit/year) and viral suppression (HIV RNA ≤ 200 copies/mL) by presence vs. absence of each MHD between 2016-2018.ResultsAmong 122,896 PWH, 67,643 (55.1%) were diagnosed with ≥ 1 MHD: 39% with depressive disorders, 28% with anxiety disorders, 10% with bipolar disorder, and 5% with schizophrenia. The prevalence of depressive and anxiety disorders increased between 2008-2018, while bipolar disorder and schizophrenia remained stable. MH multimorbidity affected 24% of PWH. From 2016-2018 (N=64,684), retention in care was marginally lower among PWH with depression or anxiety, however those with MH multimorbidity were more likely to be retained in care. PWH with bipolar disorder had marginally lower prevalence of viral suppression (aPR=0.98 [0.98-0.99]) as did PWH with MH multimorbidity (aPR=0.99 [0.99-1.00]) compared with PWH without MHD.ConclusionThe prevalence of MHD among PWH was high, including MH multimorbidity. Although retention and viral suppression were similar to people without MHD, viral suppression was lower in those with bipolar disorder and MH multimorbidity.

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Is bipolar disorder a risk factor for HIV infection?

Cited by 5 publications

References 16 publications

Psychiatric Challenges of HIV/AIDS and the Added Problems of Aging with Seropositive Status

Psychiatric Challenges of HIV/AIDS and the Added Problems of Aging with Seropositive Status

The prevalence of mental health disorders in people with HIV and the effects on the HIV care continuum

The Prevalence of Mental Health Disorders in people with HIV and the effects on the HIV Care Continuum

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