Is diabetes prevalence higher among HIV-infected individuals compared with the general population? Evidence from MMP and NHANES 2009–2010

Abstract

BackgroundNationally representative estimates of diabetes mellitus (DM) prevalence among HIV-infected adults in the USA are lacking, and whether HIV-infected adults are at increased risk of DM compared with the general adult population remains controversial.MethodsWe used nationally representative survey (2009–2010) data from the Medical Monitoring Project (n=8610 HIV-infected adults) and the National Health and Nutrition Examination Survey (n=5604 general population adults) and fit logistic regression models to determine and compare weighted prevalences of DM between the two populations, and examine factors associated with DM among HIV-infected adults.ResultsDM prevalence among HIV-infected adults was 10.3% (95% CI 9.2% to 11.5%). DM prevalence was 3.8% (CI 1.8% to 5.8%) higher in HIV-infected adults compared with general population adults. HIV-infected subgroups, including women (prevalence difference 5.0%, CI 2.3% to 7.7%), individuals aged 20–44 (4.1%, CI 2.7% to 5.5%), and non-obese individuals (3.5%, CI 1.4% to 5.6%), had increased DM prevalence compared with general population adults. Factors associated with DM among HIV-infected adults included age, duration of HIV infection, geometric mean CD4 cell count, and obesity.Conclusions1 in 10 HIV-infected adults receiving medical care had DM. Although obesity contributes to DM risk among HIV-infected adults, comparisons to the general adult population suggest that DM among HIV-infected persons may develop at earlier ages and in the absence of obesity.

Elevada frecuencia de dislipidemia en pacientes infectados por VIH en un hospital público peruano

“…Factores de riesgo cardiovascular como la alteración de los niveles lipídicos en sangre (dislipidemia), diabetes y edad avanzada, son cada vez más frecuentes en pacientes con infección por VIH (6) , quienes tendrían 50% más riesgo de sufrir un infarto de miocardio en comparación a la población general (7) .…”

The Hidden Burden of Fractures in People Living With HIV

“…Some of the risk factors commonly present in the general population appear to have increased frequency in people living with HIV. The incidence of type 2 DM is at least 1.4 times higher in this population, and it seems to occur at an earlier age when compared with the general population . In addition, HIV + men may have low testosterone levels, and the frequency of hypogonadism is increased in people living with HIV .…”

Psychosocial complications of HIV/AIDS-metabolic disorder comorbidities among patients in a rural area of southeastern United States

“…Diabetes itself increases risks for heart disease, neurological damage, kidney disease and blindness (Harris, 1998; Perkins, 2004). The 4.8% prevalence of diabetes in PLWH is comparable to the 8% prevalence of the general U.S. population (Hernandez-Romieu et al, 2016). However, diabetes complicates HIV infection and is complicated by use of antiretroviral therapies (Tsiodras, Mantzoros, Hammer, & Samore, 2000; Walli, Goebel, & Demant, 1998).…”

“…Among the HIV-related comorbidities of greatest concern are co-occurring metabolic disorders, such as diabetes mellitus (Hernandez-Romieu, Garg, Rosenberg, Thompson-Paul, & Skarbinski, 2016; Tripathi et al, 2014). Diabetes itself increases risks for heart disease, neurological damage, kidney disease and blindness (Harris, 1998; Perkins, 2004).…”