Is Doppler tissue velocity during early left ventricular filling preload independent?

Yalçın, Fatih

doi:10.1136/heart.87.4.336

Cited by 70 publications

(47 citation statements)

References 31 publications

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“…[20][21][22][23][24][25] In this study, the mitral inflow parameters were changed after HD, which is very consistent with previous studies. 26 Although the E' velocity was unchanged in some earlier studies that used sublingual nitroglycerin, the Valsalva maneuver or saline loading, 21,27 the E' velocity was suggested to be preload dependent by other studies.…”

Section: Conventional Variables To Evaluate Diastolic Functionsupporting

confidence: 80%

Preload Dependency of the Time Interval Between the Onset of Mitral Inflow and the Early Diastolic Annular Motion A Hemodialysis-Related Preload Reduction Study

Choi

Park

Shin

et al. 2007

Circ J

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Section: Conventional Variables To Evaluate Diastolic Functionsupporting

confidence: 80%

Preload Dependency of the Time Interval Between the Onset of Mitral Inflow and the Early Diastolic Annular Motion A Hemodialysis-Related Preload Reduction Study

Choi

Park

Shin

et al. 2007

Circ J

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“…In particular, the left ventricular long axis function, which predominately reflects the function of the longitudinally subendocardial and subepicardial muscle fibers, is well described by using PWTD. Furthermore, PWTD is less preload dependent and could therefore be more sensitive in detecting minor left ventricle systolic and diastolic dysfunction [17, 18]. A recent report indicates that the PWTD reproducibility and inter- and intraobserver variabilities are within acceptable limits [19].…”

Section: Introductionmentioning

confidence: 99%

Left Ventricular Dysfunction in Subjects with Mild Secondary Hyperparathyroidism Detected with Pulsed Wave Tissue Doppler Echocardiography

Iqbal¹,

Jorde

Lunde³

et al. 2005

Cardiology

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Aims: To assess left ventricular function by conventional and pulsed wave tissue Doppler (PWTD) echocardiography in subjects with mild secondary hyperparathyroidism, and to evaluate whether PWTD would be more sensitive than conventional echocardiography in detecting subtle changes in LV systolic and diastolic function. Methods: In the fifth Tromsø study (2001) serum PTH and calcium were measured in 7,954 subjects. One hundred subjects with secondary hyperparathyroidism (SHPT; serum PTH >6.40 pmol/l and serum calcium <2.40 mmol/l) and 106 control subjects with normal PTH and calcium levels and with no history of cardiovascular disease were examined at the follow-up 6–12 months later. Results: Conventional transthoracic echocardiography and PWTD of mitral annulus were successfully performed in 83 cases and 88 controls. At follow-up mean serum PTH values were 6.0 ± 2.2 versus 3.2 ± 1.3 pmol/l (p < 0.05) and mean calcium 2.28 ± 0.10 versus 2.33 ± 0.08 mmol/l (p < 0.05) in cases and controls, respectively. Unpaired t test and multiple linear regression analyses were used. No significant differences in conventional echocardiographic parameters were found. However, PWTD showed reduced systolic velocity in septal, lateral and anterior mitral annulus (p < 0.05) and also reduced early diastolic velocity in septal and anterior mitral annulus (p < 0.05). Conclusion: Subjects with mild SHPT have impaired left ventricular long axis function as evaluated by PWTD compared to conventional echocardiography. PWTD seems to be a more sensitive tool in detecting minor changes in left ventricular function and the new modality should routinely be included in studies evaluating left ventricular function, especially the long axis function.

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“…Benefits of TDI include (a) high reproducibility and accuracy, (b) excellent feasibility even in subjects with poor 2-D echocardiograms, and (c) assessment of both regional and global LV function (Alam et al 1999;Pellerin et al 2003;Nagueh, 2003). Importantly, there is evidence to suggest it is less preload dependent that standard pulsed-wave Doppler imaging (Yalcin et al 2002;Pela et al 2004b), although this remains controversial (Firstenberg et al 2001). To date no study has utilized TDI to assess segmental LV diastolic function after prolonged endurance exercise.…”

mentioning

confidence: 99%

Mitral annular myocardial velocity assessment of segmental left ventricular diastolic function after prolonged exercise in humans

George

Oxborough

Forster

et al. 2005

The Journal of Physiology

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We assessed segmental and global left ventricular (LV) diastolic function via tissue-Doppler imaging (TDI) as well as Doppler flow variables before and after a marathon race to extend our knowledge of exercise-induced changes in cardiac function. Twenty-nine subjects (age 18-62 year) volunteered to participate and were assessed pre-and post-race. Measurements of longitudinal plane TDI myocardial diastolic velocities at five sites on the mitral annulus included peak early myocardial tissue velocity (E ), peak late (or atrial) myocardial tissue velocity (A ) and the ratio E /A . Standard pulsed-wave Doppler transmitral and pulmonary vein flow indices were also recorded along with measurements of body mass, heart rate, blood pressures and cardiac troponin T (cTnT), a biomarker of myocyte damage. Pre-to post-race changes in LV diastolic function were analysed by repeated measures ANOVA. Delta scores for LV diastolic function were correlated with each other and alterations in indices of LV loading. Diastolic longitudinal segmental and mean TDI data were altered post-race such that the mean E /A ratio was significantly depressed (1.51 ± 0.34 to 1.16 ± 0.35, P < 0.05). Changes in segmental and global TDI data were not related to an elevated post-race HR, a decreased post-race pre-load or an elevated cTnT. The pulsed wave Doppler ratio of peak early transmitral flow velocity (E)/peak late (or atrial) flow velocity (A) was also significantly reduced post-race (1.75 ± 0.46 to 1.05 ± 0.30, P < 0.05); however, it was significantly correlated with post-race changes in heart rate. The lack of change in E/E from pre-to post-race (3.4 ± 0.8 and 3.3 ± 0.7, respectively) suggests that the depression in diastolic function is likely to be due to altered relaxation of the left ventricle; however, the exact aetiology of this change remains to be determined.

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Is Doppler tissue velocity during early left ventricular filling preload independent?

Cited by 70 publications

References 31 publications

Preload Dependency of the Time Interval Between the Onset of Mitral Inflow and the Early Diastolic Annular Motion A Hemodialysis-Related Preload Reduction Study

Preload Dependency of the Time Interval Between the Onset of Mitral Inflow and the Early Diastolic Annular Motion A Hemodialysis-Related Preload Reduction Study

Left Ventricular Dysfunction in Subjects with Mild Secondary Hyperparathyroidism Detected with Pulsed Wave Tissue Doppler Echocardiography

Mitral annular myocardial velocity assessment of segmental left ventricular diastolic function after prolonged exercise in humans

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