2022
DOI: 10.1073/pnas.2201709119
|View full text |Cite
|
Sign up to set email alerts
|

Is Drp1 sufficient to catalyze membrane fission?

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
3
1

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(4 citation statements)
references
References 10 publications
(23 reference statements)
0
3
1
Order By: Relevance
“…1 ) and without OS ( 1 ), indicating that neither Drp1 helical self-assembly nor GTPase activity is affected. By contrast, Roy and Pucadyil ( 3 ) do not detect comparable membrane constriction using our Drp1 construct under our purported conditions. Furthermore, in Kamerkar et al.…”
contrasting
confidence: 74%
See 3 more Smart Citations
“…1 ) and without OS ( 1 ), indicating that neither Drp1 helical self-assembly nor GTPase activity is affected. By contrast, Roy and Pucadyil ( 3 ) do not detect comparable membrane constriction using our Drp1 construct under our purported conditions. Furthermore, in Kamerkar et al.…”
contrasting
confidence: 74%
“…Whether Drp1 is self-sufficient for mitochondrial fission remains disputed ( 1 , 2 ). Roy and Pucadyil ( 3 ) assert that a lethal combination of Drp1 oxidation and phototoxicity led to failed membrane fission in our assay system ( 1 ). While we acknowledge that unresolved differences in our in vitro assays could explain the discrepancy, we rule out Drp1 oxidation and phototoxicity as relevant issues.…”
mentioning
confidence: 95%
See 2 more Smart Citations