Is evaluation by questionnaires sufficient to cover all aspects of bowel symptoms in rectal cancer patients after low anterior resection?

Asnong, Anne; D’Hoore, André; Wolthuis, Albert; Molhem, Yves Van; Geluwe, Bart Van; Devoogdt, Nele; Groef, An De; Vrieze, Tessa De; Dams, Lore; Geraerts, Inge

doi:10.1111/codi.16055

Cited by 6 publications

(1 citation statement)

References 34 publications

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“…Lastly, there may be complimentary tools, such as a stool diary, that may provide more granular details on anorectal function which were not examined in this study. 57 In conclusion, taTME was found to significantly impact fecal continence, defecatory function, and sexual function. With increased focus on PROs when assessing the multimodal treatment of rectal cancer, our findings serve to inform patients about the anticipated functional sequelae of taTME.…”

Section: Discussionmentioning

confidence: 81%

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer

Donovan,

Lee,

Ricardo

et al. 2024

Annals of Surgery

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Objective: To investigate fecal incontinence and defecatory, urinary, and sexual functional outcomes after taTME. Summary Background Data: Proctectomy for rectal cancer may result in alterations in defecatory, urinary, and sexual function that persist beyond 12 months. The recent multicenter Phase II taTME trial demonstrated the safety of taTME in patients with stage I-III tumors. Methods: Prospectively registered self-reported questionnaires were collected from 100 taTME patients. Fecal continence (FIQL, Wexner), defecatory function (COREFO), urinary function (IPSS), and sexual function (FSFI-female, IIEF-male) were assessed preoperatively (PQ), 3-4 months post-ileostomy closure (FQ1), and 12-18 months post-taTME (FQ2). Results: Among 83 patients who responded at all three time points, FIQL, Wexner, and COREFO significantly worsened post-ileostomy closure. Between FQ1 and FQ2, FIQL lifestyle and coping, Wexner, and COREFO incontinence, social impact, frequency, and need for medication significantly improved, while FIQL depression and embarrassment did not change. IPSS did not change relative to preoperative scores. For females, FSFI declined for desire, orgasm, and satisfaction between PQ and FQ1, and did not improve between FQ1 and FQ2. In males, IIEF declined with no change between FQ1 and FQ2. Conclusions: Although taTME resulted in initial decline in defecatory function and fecal continence, most functional domains improved by 12 months after ileostomy closure, without returning to preoperative status. Urinary function was preserved while sexual function declined without improvement by 18 months post-taTME. Our results address patient expectations and inform shared decision-making regarding taTME.

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Section: Discussionmentioning

confidence: 81%

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer

Donovan,

Lee,

Ricardo

et al. 2024

Annals of Surgery

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Correlation Between Mobile-Application Electronic Bowel Diary and Validated Questionnaires in Women with Fecal Incontinence

Meyer,

Iriondo-Perez,

Dyer

et al. 2024

Int Urogynecol J

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Identifying, Understanding, and Managing Fecal Urgency in Inflammatory Bowel Diseases

Caron¹,

Ghosh²,

Danese³

et al. 2023

Clinical Gastroenterology and Hepatology

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Is evaluation by questionnaires sufficient to cover all aspects of bowel symptoms in rectal cancer patients after low anterior resection?

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri butio n-NonCo mmerc ial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Cited by 6 publications

References 34 publications

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer

Correlation Between Mobile-Application Electronic Bowel Diary and Validated Questionnaires in Women with Fecal Incontinence

Identifying, Understanding, and Managing Fecal Urgency in Inflammatory Bowel Diseases

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