Is femoral trochlear dysplasia related to global joint hypermobility?

Erden, Tunay; Aksoy, Direnç Özlem; Ceylan, Hasan Hüseyin; Kapıcıoğlu, Mehmet; Bilsel, Kerem; Elmalı, Nurzat

doi:10.1016/j.jos.2018.10.008

Cited by 8 publications

(6 citation statements)

References 27 publications

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“…Previous research has found that excessive mechanical stress above the lateral condyle of the femur following patellar dislocation may result in a shallower trochlear groove and lower lateral condyle [2]. However, patients with joint hypermobility have a high incidence of femoral trochlear dysplasia [15]. In contrast to the patellar dislocation model, the patellar hypermobility model created lesser pressure on the trochlear groove and bilateral condyles in the present study.…”

Section: Discussionmentioning

confidence: 57%

Abnormal patellar pressure may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Tang

Liu

Wang

et al. 2022

Preprint

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Background: This animal study aimed to explore the effects of patellar hypermobility and patellar dislocation on the developing femoral trochlea.Methods: Seventy-two 3-week-old Wistar rats were randomly divided into three groups. The sham group (SG) underwent simple incision and suture of the skin and subcutaneous tissue; the patellar hypermobility group (PHG) underwent medial and lateral retinacular release; the patellar dislocation group (PDG) underwent plication of the medial patellofemoral retinaculum. Twelve rats in each group were euthanized at 3 and 6 weeks postoperatively, respectively, and specimens were collected. The bony sulcus angle (BSA), cartilaginous sulcus angle (CSA), trochlear sulcus depth (TSD), and thickness of the cartilage on the lateral facet (CTL), medial facet (CTM), and center (CTC) of the trochlea were measured on hematoxylin and eosin-stained sections.Results: In the PHG and PDG, the femoral condyles became blunt, the trochlear groove became shallower, and cartilage became thicker compared with the SG. Compared with the SG, the PHG and PDG had significantly larger BSA and CSA values at 3 (p < 0.05) and 6 weeks (p < 0.005), and a significantly shallower TSD (p < 0.05). At 3 weeks, all cartilage thicknesses in the PHG and the CTC and CTM in the PDG were significantly thinner than in the SG (PHG vs SG: p = 0.009 for CTL, p < 0.001 for CTM, p = 0.003 for CTC; PDG vs SG: p = 0.028 for CTC, p = 0.048 for CTM). At 6 weeks, the CTC was thicker in the PHG and PDG than the SG (PHG vs SG: p = 0.044; PDG vs SG: p = 0.027), and the CTL was thinner in the PDG than the SG (p = 0.044).Conclusion: Patellar hypermobility and patellar dislocation may result in trochlear dysplasia that worsens with age. Excessive or insufficient stress leads to trochlear dysplasia.

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Section: Discussionmentioning

confidence: 57%

Abnormal patellar pressure may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Tang

Liu

Wang

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Previous research has found that excessive mechanical loading above the lateral condyle of the femur following patellar dislocation may result in a shallower trochlear groove and lower lateral condyle [ 2 ]. However, patients with joint hypermobility have a high incidence of femoral trochlear dysplasia [ 15 ]. Ueda et al [ 16 ] observed the ultrastructure of the skin and patellofemoral ligament in dogs by histology and electron microscopy and found that patella dislocation and trochlear dysplasia were associated with overextended skin.…”

Section: Discussionmentioning

confidence: 99%

Abnormal patellar loading may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

et al. 2023

View full text Add to dashboard Cite

Background This animal study aimed to explore the effects of patellar hypermobility and patellar dislocation on the developing femoral trochlea. Methods Seventy-two 3-week-old Wistar rats were randomly divided into three groups. The sham group (SG) underwent simple incision and suture of the skin and subcutaneous tissue; the patellar hypermobility group (PHG) underwent medial and lateral retinacular release and pie-crusting technique for the patellar ligament; the patellar dislocation group (PDG) underwent plication of the medial patellofemoral retinaculum. Twelve rats in each group were euthanized at 3 and 6 weeks postoperatively, respectively, and specimens were collected. The bony sulcus angle (BSA), cartilaginous sulcus angle (CSA), trochlear sulcus depth (TSD), and thickness of the cartilage on the lateral facet (CTL), medial facet (CTM), and center (CTC) of the trochlea were measured on hematoxylin and eosin-stained sections. Results In the PHG and PDG, the femoral condyles became blunt, the trochlear groove became shallower, and cartilage became thicker compared with the SG. Compared with the SG, the PHG and PDG had significantly larger BSA and CSA values at 3 (p < 0.05) and 6 weeks (p < 0.005), and a significantly shallower TSD (p < 0.05). At 3 weeks, all cartilage thicknesses in the PHG and the CTC and CTM in the PDG were significantly thinner than in the SG (PHG vs. SG: p = 0.009 for CTL, p < 0.001 for CTM, p = 0.003 for CTC; PDG vs. SG: p = 0.028 for CTC, p = 0.048 for CTM). At 6 weeks, the CTC was thicker in the PHG and PDG than the SG (PHG vs. SG: p = 0.044; PDG vs. SG: p = 0.027), and the CTL was thinner in the PDG than the SG (p = 0.044). Conclusion Patellar hypermobility and patellar dislocation may result in trochlear dysplasia that worsens with age. Excessive or insufficient loading leads to trochlear dysplasia.

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“…Previous research has found that excessive mechanical loading above the lateral condyle of the femur following patellar dislocation may result in a shallower trochlear groove and lower lateral condyle [2]. However, patients with joint hypermobility have a high incidence of femoral trochlear dysplasia [15]. Ueda et al [16] observed the ultrastructure of the skin and patellofemoral ligament in dogs by histology and electron microscopy, and found that patella dislocation and trochlear dysplasia were associated with overextended skin.…”

Section: Discussionmentioning

confidence: 99%

Abnormal patellar loading may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Tang

Liu

Wang

et al. 2022

Preprint

View full text Add to dashboard Cite

Background: This animal study aimed to explore the effects of patellar hypermobility and patellar dislocation on the developing femoral trochlea. Methods: Seventy-two 3-week-old Wistar rats were randomly divided into three groups. The sham group (SG) underwent simple incision and suture of the skin and subcutaneous tissue; the patellar hypermobility group (PHG) underwent medial and lateral retinacular release; the patellar dislocation group (PDG) underwent plication of the medial patellofemoral retinaculum. Twelve rats in each group were euthanized at 3 and 6 weeks postoperatively, respectively, and specimens were collected. The bony sulcus angle (BSA), cartilaginous sulcus angle (CSA), trochlear sulcus depth (TSD), and thickness of the cartilage on the lateral facet (CTL), medial facet (CTM), and center (CTC) of the trochlea were measured on hematoxylin and eosin-stained sections. Results: In the PHG and PDG, the femoral condyles became blunt, the trochlear groove became shallower, and cartilage became thicker compared with the SG. Compared with the SG, the PHG and PDG had significantly larger BSA and CSA values at 3 (p < 0.05) and 6 weeks (p < 0.005), and a significantly shallower TSD (p < 0.05). At 3 weeks, all cartilage thicknesses in the PHG and the CTC and CTM in the PDG were significantly thinner than in the SG (PHG vs SG: p = 0.009 for CTL, p < 0.001 for CTM, p = 0.003 for CTC; PDG vs SG: p = 0.028 for CTC, p = 0.048 for CTM). At 6 weeks, the CTC was thicker in the PHG and PDG than the SG (PHG vs SG: p = 0.044; PDG vs SG: p = 0.027), and the CTL was thinner in the PDG than the SG (p = 0.044). Conclusion: Patellar hypermobility and patellar dislocation may result in trochlear dysplasia that worsens with age. Excessive or insufficient loading leads to trochlear dysplasia.

show abstract

Is femoral trochlear dysplasia related to global joint hypermobility?

Cited by 8 publications

References 27 publications

Abnormal patellar pressure may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Abnormal patellar pressure may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Abnormal patellar loading may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

Abnormal patellar loading may lead to femoral trochlear dysplasia: an experimental study of patellar hypermobility and patellar dislocation in growing rats

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