Is Helicobacter pylori a Cause of Nonulcer Dyspepsia?

Talley, Nicholas J.

doi:10.1007/978-3-642-75315-2_53

Cited by 23 publications

(24 citation statements)

References 32 publications

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“…There is a clear association between H . pylori infection and chronic active gastritis (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). However, only a few studies in children consider both gastric antrum and body when determining the grade of gastritis (10, l l ) , and post-treatment follow-up studies are scarce.…”

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confidence: 99%

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A Long-Term Follow-up after Treatment with Colloidal Bismuth Subcitrate and Tinidazole

Ashorn

Ruuska

Karikoski

et al. 1994

Scandinavian Journal of Gastroenterology

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The connection between dyspeptic symptoms and Helicobacter pylori infection was studied prospectively in 21 children treated for verified H. pylori infection with bismuth subcitrate and tinidazole. Gastroscopy with biopsy was performed before and a mean of 4 months after discontinuation of the treatment. A second post-treatment check with determination of H. pylori antibodies and serum pepsinogen 1 level was made a mean of 1.5 years after cessation of treatment. The therapy given cleared the bacteria in 67% of the patients. No significant difference in symptoms was observed between treatment successes and failures. The histopathologic diagnosis of H. pylori infection was accompanied by positive IgG serology in 15 (75%) of the 20 patients tested, and a decrease in antibody levels was observed in children with successful eradication. Serum pepsinogen 1 seemed to be even a better marker in the follow-up. The healing of acute and also to some extent of chronic gastritis took place closely after successful eradication. Our results suggest that healing of H. pylori-induced gastritis should be confirmed at reendoscopy only, independent of the symptoms.

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confidence: 99%

“…An increased frequency of Helicobacter pylori infection has been shown in patients with dyspepsia (1). Information as to its connection with gastrointestinal symptoms is scarce, however, especially in the pediatric population (2-4).…”

mentioning

confidence: 99%

A Long-Term Follow-up after Treatment with Colloidal Bismuth Subcitrate and Tinidazole

Ashorn

Ruuska

Karikoski

et al. 1994

Scandinavian Journal of Gastroenterology

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“…Amongst patients with NUD, 30% to 50% have H pylori infection and underlying chronic gastritis histologically. 42,43 No clear cut link has been documented between H pylori and any specific symptom profile or pathophysiologic mechanism in NUD.…”

Section: N O N -U L C E R D Y S P E P S I Amentioning

confidence: 99%

Management of dyspepsia

Abeygunasekera

Talley

2002

Compr Ther

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“…It is estimated that 20% to 40% of the adult population in the developed world is affected by complaints of indigestion or dyspepsia [1]. Over the past few years a number of studies have tried to address this question; the results of these studies have been equivocal, at best [2,3]. These studies have been criticized because of their small size and study design.…”

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confidence: 98%

The association of Helicobacter pylori infection with nonulcer dyspepsia

Wanke

2000

Curr Infect Dis Rep

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Is Helicobacter pylori a Cause of Nonulcer Dyspepsia?

Cited by 23 publications

References 32 publications

A Long-Term Follow-up after Treatment with Colloidal Bismuth Subcitrate and Tinidazole

A Long-Term Follow-up after Treatment with Colloidal Bismuth Subcitrate and Tinidazole

Management of dyspepsia

The association of Helicobacter pylori infection with nonulcer dyspepsia

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