2022
DOI: 10.1080/07853890.2022.2089911
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Is hypertension associated with arthritis? The United States national health and nutrition examination survey 1999–2018

Abstract: Objective Hypertension and arthritis are two common diseases in the general population, with multiple common risk factors. This study aimed to assess the association between hypertension (HTN) and arthritis. Patients and methods This cohort study included 48,372 eligible non-pregnant participants aged ≥ 20 years who had valid data on hypertension and arthritis from the National Health and Nutrition Examination Survey (NHANES) 1999–2018. The association between hypertens… Show more

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Cited by 22 publications
(11 citation statements)
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“…One of the possible mechanisms behind the causality of the relationship between OA and CVD is that patients with OA may have increased inflammatory mediators, such as tumor necrosis factor‐α, interleukin‐17, monocyte chemoattractant protein‐1, and interleukin‐6. These mediators have been studied for their involvement in hypertension 36–38 and are considered predictors of arterial stiffness and endothelial dysfunction, 39 and are associated with accelerated atherosclerosis and increased cardiovascular mortality 40 . C‐reactive protein, which is a highly sensitive systemic marker of inflammation, is used to evaluate subclinical inflammatory processes underlying atherothrombotic events and has also emerged as a potential prognostic factor for HF 41–43 .…”
Section: Discussionmentioning
confidence: 99%
“…One of the possible mechanisms behind the causality of the relationship between OA and CVD is that patients with OA may have increased inflammatory mediators, such as tumor necrosis factor‐α, interleukin‐17, monocyte chemoattractant protein‐1, and interleukin‐6. These mediators have been studied for their involvement in hypertension 36–38 and are considered predictors of arterial stiffness and endothelial dysfunction, 39 and are associated with accelerated atherosclerosis and increased cardiovascular mortality 40 . C‐reactive protein, which is a highly sensitive systemic marker of inflammation, is used to evaluate subclinical inflammatory processes underlying atherothrombotic events and has also emerged as a potential prognostic factor for HF 41–43 .…”
Section: Discussionmentioning
confidence: 99%
“…The de nition of arthritis refers to the two questions in the questionnaire survey, ' whether there is medical staff to tell whether there is arthritis ' and ' what kind of arthritis ' to de ne whether there is arthritis and the type of arthritis (7). We further divided arthritis patients into three groups: RA, OA and other types.…”
Section: De Nition Of Arthritismentioning
confidence: 99%
“…Arthritis is also a health problem that poses a great threat to the quality of life of middle-aged and elderly people (7). About half of American adults will suffer from arthritis by 2040 (8).…”
Section: Introductionmentioning
confidence: 99%
“…About 20% of the general population affected by hyperuricemia, which might be more prominent in male and aged population 7. Prior research has consistently shown a significant correlation between arthritis, particularly OA and rheumatoid arthritis (RA), and hypertension 8. The intricate relationship between metabolic processes and arthritis, alongside the interplay between metabolic and immunological factors, is garnering heightened attention.…”
Section: Introductionmentioning
confidence: 99%