“…Haemolysed red blood cells are the probable source of the iron, and also of the zinc (Berfenstam 1952), but when iron is set free inside the body of an adult by the breakdown of red cells due to the administration of phenylhydrazine (McCance and Widdowson, 1937a) or in patients suffering from severe haemolytic anaemia (McCance and Widdowson, 1943;Granick, 1949), no significant amount of the iron is excreted. Indeed, iron once incorporated into the body of an adult is not excreted by the intestine in more than traces, and the amount of iron in the body is regulated by controlled absorption (McCance and Widdowson, 1937b;Maddock and Heath, 1939).…”