Is it time to perform the first human head transplant? Comment on the CSA (cephalosomatic anastomosis) paper by Ren, Canavero, and colleagues

Application of“Spinal cord fusion” in spinal cord injury repair and its neurological mechanism

“…According to the literature, two neuronal systems from the brain to the spinal cord regulate the voluntary motor function of the extremities. The first system, known as the cortico-trunco-reticulo-propriospinal pathway (CTRPS), is a critical component of the spinal system, involving a segmental nervous system [ 61 ]. This multisynaptic pathway from the brain to the spinal cord connects nearby neurones sequentially over short segments from the cerebral cortex to the spinal cord to control extremity movements [ 61 ].…”

“…The first system, known as the cortico-trunco-reticulo-propriospinal pathway (CTRPS), is a critical component of the spinal system, involving a segmental nervous system [ 61 ]. This multisynaptic pathway from the brain to the spinal cord connects nearby neurones sequentially over short segments from the cerebral cortex to the spinal cord to control extremity movements [ 61 ]. The other system, called the pyramidal tract (PyT), comprises long, fast signal-transmitting neurones that connect neurons in the cerebral cortex to those in the spinal cord, enabling the rapid transmission of motor commands.…”

“…When the spinal cord is injured, the recovery of functional PyT through axon regrowth along the transected long neuronal tracts is very slow because axon regrowth can only be accomplished by regenerating long distances from the brain to the spinal cord. In contrast, the CTRPS, which is a shorter, multi-neuronal pathway, can quickly regrow and establish connections with spinal cord segments, thereby re-establishing the multi-neuronal pathways responsible for controlling movement and sensation [ 61 ].…”

“…Previous attempts to connect the transected cords using various biological combinations had been unsuccessful. However, based on historical investigations and experimental research, scholars worldwide have challenged this long-held viewpoint, demonstrating that it is incorrect [ 61 ]. Despite considerable controversy, the feasibility and potential role of SCF in SCI remain controversial.…”

RevSALUS: o nascimento de uma revista para promover a inovação, interdisciplinaridade e integridade científica na saúde

“…Ausman 2018). E porque acredito que tudo na ciência não tem fronteiras estanques entre as áreas, mesmo sem ver no presente a ligação, a 10 de abril de 2019 o mundo conheceu a primeira imagem de um buraco negro supermaciço, comprovando 104 anos depois a teoria da Relatividade Geral de Einstein, apresentada em 1915.…”