Is modified embryo transfer technique related to an increased pregnancy rate?

Lee, Fa‐Kung; Hsu, Yueh-Han; Wang, Peng-Hui

doi:10.1097/jcma.0000000000000491

Cited by 2 publications

(2 citation statements)

References 21 publications

(45 reference statements)

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“…In humans, the uterus becomes favorable to embryo implantation between days 19 and 23 of the menstrual cycle, a period known as the implantation window 2 . At present, implantation is the critical step that limits the success of in vitro fertilization (IVF) techniques 3 .…”

Section: Introductionmentioning

confidence: 99%

Is the length of time between endometrial scratching and embryo transfer important for pregnancy success? An observational study

Ueno

Salgado

Ejzenberg

et al. 2023

Rev. Assoc. Med. Bras.

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OBJECTIVE: This study sought to evaluate the influence of time (early <90 days and late >90 days) and endometrial injury on pregnancy success. METHODS: This is a retrospective study in which all infertile women who underwent at least one in vitro fertilization cycle at Clinica Gera between 2010 and 2015 were considered for inclusion. We included patients with a normal ovarian reserve and regular menses at intervals of up to 30 days. A total of 315 patient files were reviewed, and the study group was composed of patients who faced fertility issues and had male-caused infertility or idiopathic infertility. Also, women with male or unknown cause of infertility who have performed endometrial biopsy and have undergone embryo transfer up to 180 days after this procedure between 2010 and 2015 were included. The patients were divided into two groups according to the interval between biopsy and embryo transfer: group 1 (early-an interval of <90 days) and group 2 (late-an interval of >90 days and up to 180 days). RESULTS: The results were superior for the group with an interval of less than 90 days relative to the group with an interval of more than 90 days (p<0.04). The pregnancy rates for group 1 and group 2 were 58.5% and 43.4%, respectively. The odds ratio for pregnancy success was 1.63 (95% confidence interval: 1.04 to 2.55). CONCLUSION: The early transfer of embryos (<90 days) may produce better results with a high rate of pregnancy. Further studies are necessary to identify the mechanism involved in this phenomenon.

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Section: Introductionmentioning

confidence: 99%

Is the length of time between endometrial scratching and embryo transfer important for pregnancy success? An observational study

Ueno

Salgado

Ejzenberg

et al. 2023

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

show abstract

“…Further randomized controlled trials are needed to provide more evidence, in addition to a further study to identify individuals that benefit more. After the improvement of the quality and quantity of oocyte, the following IVF/ICSI-ET becomes much more critical, since implantation failure is also a key step during the ART, resulting in the urgent need to determine the key factor influencing embryo implantation [15]. Lv et al analyzed single-cell sequencing data and further explored the transcriptomic changes in endometrial stromal cells after coculturing with trophoblast cells to show 1783 upregulated genes and 569 down regulated genes in the cocultured embryos [16].…”

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confidence: 99%