Is molecular testing of salivary gland FNA specimens ready for prime time?

Abstract

With improvements in the molecular characterization of salivary gland neoplasms, fine‐needle aspiration specimens, including smears and cell blocks, are amenable to molecular testing for defining alterations, providing a specific diagnosis in many cases, and guiding management in a preoperative setting. Molecular testing can be particularly beneficial and complementary when used within the framework of the Milan system, as the results can further refine the risk of malignancy.