The temporomandibular joint (TMJ) has a complex and unique anatomy. When disarranged, it may produce a constellation of symptoms and dysfunction, leading to morbidity. The causes of TMJ dysfunction are numerous but often present with similar clinical signs and symptoms. In this series, we included a review of normal anatomy and a review of the pathophysiology with assessment of the most common TMJ dysfunctions, including myofascial pain, internal derangements of the articular disk, osteoarthrosis, among others. The authors present the last of a 3-part educational series on the TMJ, addressing treatment strategies for these disorders.