Is olive oil good for you? A systematic review and meta-analysis on anti-inflammatory benefits from regular dietary intake

Fernandes, João; Fialho, Mónica; Santos, Rodrigo Cardoso; Peixoto-Plácido, Catarina; Madeira, Teresa; Sousa-Santos, Nuno; Virgolino, Ana; Santos, Osvaldo; Carneiro, António Vaz

doi:10.1016/j.nut.2019.110559

Cited by 85 publications

(61 citation statements)

References 56 publications

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“…Olive oil as part of a Mediterranean diet, fish oil, or medium-chain fatty acids are reported to improve metabolic abnormalities. [41][42][43] Future studies should consider the type of lipids consumed.…”

Section: Discussionmentioning

confidence: 99%

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Kusakabe

Yokota

Shimizu

et al. 2020

BMJ Open Diab Res Care

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IntroductionTreatment using sodium-glucose cotransporter (SGLT) 2 inhibitor and low-carbohydrate diet (LCD) for obesity and type 2 diabetes are similar in terms of carbohydrate limitation. However, their mechanisms of action differ, and the effects on the body remain unclear. We investigated the effects of SGLT2 inhibitor and LCD on body composition and metabolic profile using the db/db mouse model for obesity and type 2 diabetes.Research design and methodsEight-week-old male db/db mice were divided into four groups: mice receiving normal diet and vehicle or canagliflozin (Cana) administration and mice receiving LCD and vehicle or Cana administration for 8 weeks. Consumed calories were adjusted to be equal among the groups.ResultsBoth Cana administration and LCD feeding resulted in significant weight gain. Cana administration significantly decreased plasma glucose levels and increased plasma insulin levels with preservation of pancreatic β cells. However, LCD feeding did not improve plasma glucose levels but deteriorated insulin sensitivity. LCD feeding significantly reduced liver weight and hepatic triglyceride content; these effects were not observed with Cana administration. Combined treatment with LCD did not lead to an additive increase in blood β-ketone levels.ConclusionsSGLT2 inhibitors and LCD exert differential effects on the body. Their combined use may achieve better metabolic improvements in obesity and type 2 diabetes.

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Section: Discussionmentioning

confidence: 99%

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Kusakabe

Yokota

Shimizu

et al. 2020

BMJ Open Diab Res Care

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“…A recent meta-analysis of randomized controlled trials evaluated regular olive oil intake effects on inflammation [122]. The authors reported a decrease in the levels of IL-6, tumor necrosis factor-α (TNF-α) and CRP, the three plasmatic inflammatory indicators considered.…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Bioactive Compounds and Quality of Extra Virgin Olive Oil

Jiménez-López

Carpena

Gallardo-Gómez

et al. 2020

Foods

310

235

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(1) Background: Extra virgin olive oil (EVOO) is responsible for a large part of many health benefits associated to Mediterranean diet as it is a fundamental ingredient of this diet. The peculiarities of this golden, highly valued product are in part due to the requirements that must be met to achieve this title, namely, it has to be obtained using exclusively mechanical procedures, its free acidity cannot be greater than 0.8%, it must not show sensory defects, and it has to possess a fruity taste. (2) Methods: All these characteristics are key factors to EVOO quality, thus the chemical composition of these many health-promoting compounds, such as unsaturated fatty acids (which are also the major compounds, especially oleic acid), as well as minor components such as tocopherols or phenolic compounds (which behave as natural antioxidants) must be preserved. (3) Results: Due to the presence of all these compounds, the daily consumption of EVOO entails health benefits such as cardioprotective, antioxidant, anti-inflammatory, anti-tumor properties or acting as regulator of the intestinal microbiota, among others. (4) Conclusions: Taking all together, conserving EVOO chemical composition is essential to preserve its properties, so it is worth to control certain factors during storage like exposure to light, temperature, oxygen presence or the chosen packaging material, to maintain its quality and extend its shelf-life until its consumption.

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“…MedDiet consists of a large number of bioactive ingredients, including high content of olive oil and fish rich in omega-3 and omega-9. Both fatty acids have anti-inflammatory [ 2 ] and pro-resolutive effects [ 104 ], acting pharmacologically and on biochemical targets [ 177 ]. The omega-3 and omega-9 show metabolic and immune regulatory effects, modulating intracellular pathways and transcription factor activation.…”

Section: Discussionmentioning

confidence: 99%

“…Over the years, many scientific articles, newspapers, and magazines have promoted the beneficial role of the Mediterranean diet (MedDiet), including association with a decreased incidence of cardiovascular events, diabetes, metabolic syndrome, and breast cancer [ 1 , 2 , 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Mediterranean Diet: Lipids, Inflammation, and Malaria Infection

Silva

Moraes

Gonçalves-de-Albuquerque

2020

IJMS

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The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions of people around the globe. The parasite Plasmodium causes the disease. The metabolic and inflammatory alterations in the severe forms have damaging consequences to the host. The lipid content in the MedDiet holds anti-inflammatory and pro-resolutive features in the host and have detrimental effects on the Plasmodium. The lipids from the diet impact the balance of pro- and anti-inflammation, thus, lipids intake from the diet is critical to parasite elimination and host tissue damage caused by an immune response. Herein, we go into the cellular and molecular mechanisms and targets of the MedDiet fatty acids in the host and the parasite, reviewing potential benefits of the MedDiet, on inflammation, malaria infection progression, and clinical outcome.

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Is olive oil good for you? A systematic review and meta-analysis on anti-inflammatory benefits from regular dietary intake

Cited by 85 publications

References 56 publications

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Bioactive Compounds and Quality of Extra Virgin Olive Oil

Mediterranean Diet: Lipids, Inflammation, and Malaria Infection

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