Is oral dysaesthesia a somatic symptom disorder?

Kwong, Kenelm; Yeoh, Sue Ching; Balasubramaniam, Ramesh

doi:10.1111/jop.13064

Cited by 6 publications

(3 citation statements)

References 48 publications

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“…Oral dysesthesia is defined as an abnormal sensation in the oral cavity, such as a burning feeling, that is not associated with any abnormal clinical findings [53]. It is often described as a subjective feeling of oral tingling or pain, and it can be a diagnostic challenge for many clinicians.…”

Section: Oral Dysesthesiamentioning

confidence: 99%

Pathogenesis of Oral Toxicities Associated with Targeted Therapy and Immunotherapy

Villa

Kuten‐Shorrer

2023

IJMS

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Targeted therapy and immunotherapy have redefined cancer treatment. While they have enhanced tumor response and improved survival rates in many cancer types, toxicities continue to occur, and these often involve the oral cavity. Broadly reported as “mucositis” or “stomatitis,” oral toxicities induced by targeted therapies differ clinically and mechanistically from those associated with conventional chemotherapy. Manifesting primarily as mucosal lesions, salivary gland hypofunction, or orofacial neuropathies, these oral toxicities may nonetheless lead to significant morbidity and impact patients’ quality of life, thereby compromising clinical outcomes. We conclude that familiarity with the spectrum of associated toxicities and understanding of their pathogenesis represent important areas of clinical research and may lead to better characterization, prevention, and management of these adverse events.

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Section: Oral Dysesthesiamentioning

confidence: 99%

Pathogenesis of Oral Toxicities Associated with Targeted Therapy and Immunotherapy

Villa

Kuten‐Shorrer

2023

IJMS

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“…Psychiatric comorbidities in BMS were found in 22.2% to 71.6% [1,2,4,9], although the comorbidity of severe psychiatric disorders such as schizophrenia (0.8%) and bipolar disorders (1.6%) are rare [9]. The previous study revealed that depression and anxiety affect pain or unpleasant discomfort in BMS as well as chronic pain in the other body parts [10]. A negative aspect of pain perception itself also would induce anxiety and depression [11].…”

Section: Introductionmentioning

confidence: 97%

Clinical Features and Variations of Pain Expressions in 834 Burning Mouth Syndrome Patients With or Without Psychiatric Comorbidities

Takao,

Watanabe,

Nayanar

et al. 2023

Cureus

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Burning mouth syndrome (BMS) is characterized as chronic burning pain or unpleasant discomfort in the oral region without any corresponding clinical abnormalities. The aim of this study is to investigate the difference in clinical features and the variations of pain expressions between BMS patients with and without psychiatric comorbidities. MethodologyThe patients with BMS who first visited between April 2016 and March 2020 were involved and the clinical data including the presence of psychiatric comorbidities and scores of self-rating depression scale (SDS), pain catastrophizing scale (PCS), and pain quality from short-form McGill pain questionnaire (SF-MPQ) were collected retrospectively. ResultsIn 834 patients with BMS (700 females, 63.9 ± 13.1 years old), 371 patients (44.5%) had psychiatric comorbidities. There was no significant between-group difference in demographic data. However, significantly higher scores were observed in SDS (p < 0.001) and PCS (p < 0.001) in the patients with psychiatric comorbidities. Moreover, the patients with psychiatric comorbidities showed significantly stronger pain intensity (p < 0.001) besides higher scores of each descriptor in SF-MPQ. In addition, they had chosen more descriptors in SF-MPQ (p < 0.001); furthermore, the number of selected pain descriptors showed a stronger correlation with PCS than with SDS regardless of the presence of psychiatric comorbidities. ConclusionBMS patients may complain of various pain expressions regardless of the psychiatric comorbidities; however, more severe complaints relating to high pain catastrophizing are more likely in patients with psychiatric comorbidities. These results suggested that underlying anxiety exacerbated the variety of pain expressions in BMS patients with psychiatric comorbidities.

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“…Patients with this syndrome are present to a variety of health professionals, such as oral surgeons, otolaryngologists and dermatologists (2). Since the pathophysiological origins of BMS remain unknown and comorbid psychiatric history are frequently observed, patients are occasionally referred to psychiatrists where its "medically unexplained" burning pain is regarded as a form of somatic symptom disorder (SSD) (3,4). Subsequently, these patients would be treated by psychopharmacotherapy with antidepressants or by other psychotherapeutic management (5).…”

Section: Introductionmentioning

confidence: 99%

Case Report: Hidden Oral Squamous Cell Carcinoma in Oral Somatic Symptom Disorder

Suga

Takenoshita

et al. 2021

Front. Psychiatry

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Background: Burning mouth syndrome (BMS) is a common condition of predominant oral pain without evident cause, that maxillofacial surgeons and otolaryngologists often refer to psychiatrists as somatic symptom disorder. In very rare cases, its typical burning symptom mimics those of other diseases in which serious fatal comorbidities may be missed. We encountered three rare cases of oral squamous cell carcinoma (OSCC) with the first symptom of burning tongue.Case Presentation: Case 1: A 68-year-old woman had burning pain on the left lingual margin for 8 years. Antidepressant treatment was not efficacious. Cytology and biopsy revealed OSCC. Case 2: A 70-year-old man had burning sensation and paralysis of the tongue for 6 months. Magnetic resonance imaging (MRI) revealed a 37 × 23-mm mass under the floor of the mouth and enlargement of lymph nodes on both sides. Case 3: A 90-year-old man had burning sensation of the tongue for 1 year. MRI revealed a 12 × 12-mm mass on the mandible with bone absorption.Conclusion: This case series suggests that psychiatrists must always be careful in regarding BMS as somatic symptom disorder and be cautious of the possibility of OSCC, especially in elderly patients.

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Is oral dysaesthesia a somatic symptom disorder?

Cited by 6 publications

References 48 publications

Pathogenesis of Oral Toxicities Associated with Targeted Therapy and Immunotherapy

Pathogenesis of Oral Toxicities Associated with Targeted Therapy and Immunotherapy

Clinical Features and Variations of Pain Expressions in 834 Burning Mouth Syndrome Patients With or Without Psychiatric Comorbidities

Case Report: Hidden Oral Squamous Cell Carcinoma in Oral Somatic Symptom Disorder

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