Is pituitary failure the real therapeutic target in septic shock?

Kouatli, Yasser

doi:10.1016/j.mehy.2009.09.032

Medical Hypotheses

2010

DOI: 10.1016/j.mehy.2009.09.032

|View full text |Cite

Is pituitary failure the real therapeutic target in septic shock?

Yasser Kouatli

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2017

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Neuroendocrine Derangements in Early Septic Shock

Schurr

Szumita

DeGrado

2017

Shock

View full text Add to dashboard Cite

Septic shock is a leading cause of mortality in intensive care units throughout the world. While this disease state represents a highly complex pathophysiology involving numerous organ systems, the early approach to care includes adequate hemodynamic support traditionally achieved via infusions of vasoactive medications after adequate fluid resuscitation. Relative adrenal and vasopressin deficiencies are a common feature of septic shock that contribute to impaired hemodynamics. Hydrocortisone and vasopressin are endocrine system hormone analogues that target the acute neuroendocrine imbalance associated with septic shock. This clinically focused annotated review describes the pathophysiological mechanisms behind their use and explores the potential clinical roles of early administration and synergy when combined.

show abstract

Neuroendocrine Derangements in Early Septic Shock

Schurr

Szumita

DeGrado

2017

Shock

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Is pituitary failure the real therapeutic target in septic shock?

Cited by 1 publication

References 32 publications

Neuroendocrine Derangements in Early Septic Shock

Neuroendocrine Derangements in Early Septic Shock

Contact Info

Product

Resources

About