Is Pulmonary Function Affected by Bilateral Dual Transversus Abdominis Plane Block? A Randomized, Placebo-Controlled, Double-Blind, Crossover Pilot Study in Healthy Male Volunteers

Petersen, Maria Hvidberg; Elers, Jimmi; Børglum, Jens; Belhage, Bo; Mortensen, Jann; Maschmann, Christian

doi:10.1097/aap.0b013e3182330b95

Cited by 9 publications

(7 citation statements)

References 17 publications

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“…[17,18] This is consistent with the results of our study. Zones 1 and 4 are located at levels T6 to T8, zone 7 is located at level L1.…”

Section: Discussionsupporting

confidence: 93%

“…Most of the previous studies [7,17,18] only reported and analyzed the comparison of different plane levels, but never analyzed the diffusion of the block from midline to the back. If we use TAP block for postoperative analgesia purpose without knowing the diffusion pattern, for example, using TAP block on an upper lateral abdominal incision, it likely to cause poor analgesia results.…”

Section: Discussionmentioning

confidence: 99%

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Analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block

Jiang²,

Tang³

et al. 2017

Medicine

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Background: To evaluate the analgesic efficacy on defined areas of the abdomen and back after ultrasound-guided subcostal transversus abdominis plane (TAP) block using 0.25% levobupivacaine 0.5 mL/kg.Methods: Twenty patients undergoing elective laparoscopic cholecystectomy, between 20 and 60 years of age with operative time <1 hour, received subcostal TAP block using 0.25% levobupivacaine 0.5 mL/kg on the left side. Surgery started after 1 hour of observation. Sensory assessment was undertaken using pinprick and 75% ethyl alcohol at 10, 20, 30 minutes, 1, 3, and 12 hours after TAP block at 19 testing zones that were divided by anatomic landmark lines on the abdomen and the back. Efficacy of zone was defined as loss of cold temperature sensation or loss of pinprick pain sensation in more than 50% patients in that testing zone. Duration was determined by analgesia and loss of temperature sensation beginning within 30 minutes of TAP block placement lasting until time points of 1, 3, and 12 hours. All of the testing zones were divided as Group I effective at 20 minutes in less than 50% patients (0%-50%), Group II 50% to 70% patients, Group III 70% to 90% patients, and Group IV 90% to 100% patients.Results: Twenty patients meeting the study requirements were included. At each time point, the efficacies among 4 groups were significantly different. Subcostal TAP had good efficacy and stable duration in zones 1, 2, 3, 5, and 6.Conclusion: Subcostal TAP block with 0.25% levobupivacaine 0.5 mL/kg dose provided effective analgesia in the anterior abdominal wall between medioventral line to anterior axillary line except the lateral upper abdominal region.Abbreviation: TAP = transversus abdominis plane.

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“…[17,18] This is consistent with the results of our study. Zones 1 and 4 are located at levels T6 to T8, zone 7 is located at level L1.…”

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block

Jiang²,

Tang³

et al. 2017

Medicine

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“…Niraj et al studied the analgesic effect of subcostal transversus abdominis plane catheters versus epidural catheters, and in that study 45% of TAP catheters had to be re-sited within the first 24 hours after surgery [13]. In a study of pulmonary function in healthy volunteers that had bilateral TAP blockade, 2 out of 11 volunteers had bilateral block failure [14]. We should have anticipated problems with block failure and catheter displacements and taken this into account in our sample size calculation.…”

Section: Discussionmentioning

confidence: 99%

Bilateral transversus abdominis plane (TAP) block with 24 hours ropivacaine infusion via TAP catheters: A randomized trial in healthy volunteers

et al. 2013

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BackgroundThe analgesic effect of a TAP block has been investigated in various surgical settings. There are however limited information about block level and block duration. Furthermore, there is a lack of information about continuous TAP block after ultrasound-guided posterior TAP blocks.The aim of this double-blind randomized study was therefore to investigate the effect of an ultrasound-guided posterior TAP block with 24 hours local anesthetic infusion via a TAP catheter.MethodsIn this randomized study 8 male volunteers received a bilateral TAP block (20 mLs 0.5% ropivacaine) and were allocated to receive active infusion (ropivacaine 0.2% 5 mL/hr) via a TAP catheter on one side and placebo infusion on the other side. Primary outcome: Dermatomal sensory block involvement after 24 hours evaluated with pinprick. Secondary outcomes: Sensory block involvement evaluated with cold test and heat-pain detection thresholds (HPDT) on the abdominal wall. Assessment points: 15 min before block performance and 1, 4, 8, 12 and 24 hours after block performance.ResultsThe TAP block primarily involved sensory changes in the Th10 to Th12 dermatomes. On the placebo side there was a decrease in extension beginning at 4–8 hours after block performance and with no detectable effect beyond 12 hours. Median number of dermatomes anesthetized (pinprick) at 24 hours after block performance was 1.5 (0–3) on the active side compared with 0 (0–0) on the placebo side (P = 0.039).There were no statistical significant between-side differences in HPDT measurements at 24 hours after block performance.ConclusionsThe spread of sensory block following ultrasound-guided posterior TAP block is partly maintained by a continuous 24 hour ropivacaine infusion through a TAP catheter.Trial registrationThe study was registered at NCT01577940

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“…Preincisional timing for injection has yet to be tested in randomized trials. 298,299,302,303,[306][307][308][309] Reported complications include intraperitoneal injection or hemorrhage, transient femoral nerve palsy, and local anesthetic toxicity. [310][311][312] In summary,…”

Section: Transversus Abdominis Plane Blockmentioning

confidence: 99%

Postoperative Pain and Other Acute Pain Syndromes

Hanna

Ouanes

Tomas

2014

Practical Management of Pain

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Is Pulmonary Function Affected by Bilateral Dual Transversus Abdominis Plane Block? A Randomized, Placebo-Controlled, Double-Blind, Crossover Pilot Study in Healthy Male Volunteers

Abstract: The administration of ultrasound-guided bilateral dual TAP blocks does not result in clinically relevant or statistically significant changes in the pulmonary function in healthy male subjects.

Cited by 9 publications

References 17 publications

Analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block

Analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block

Bilateral transversus abdominis plane (TAP) block with 24 hours ropivacaine infusion via TAP catheters: A randomized trial in healthy volunteers

Postoperative Pain and Other Acute Pain Syndromes

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