Is Radiographic Osteoporotic Hip Morphology A Predictor For High Mortality Following Intertrochanteric Femur Fractures?

Okkaoğlu, Mustafa Caner; Özdemir, Erdi; Yaradilmis, Ugur; Altay, Murat

doi:10.1016/j.injury.2021.01.033

Cited by 2 publications

(2 citation statements)

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“…Few studies have explored the relationship between bone density and mortality in the context of postoperative death after HF. As described in some studies [ 32 – 35 ], this may be due to the challenges of obtaining dual-energy X-ray absorptiometry (DXA) scans in the acute setting for HF patients. Radiological parameters (such as cortical thickness [ 34 , 35 ], Singh index, and Dorr classification [ 32 ]) were revealed to be associated with osteoporosis or mortality risks.…”

Section: Discussionmentioning

confidence: 99%

“…As described in some studies [ 32 – 35 ], this may be due to the challenges of obtaining dual-energy X-ray absorptiometry (DXA) scans in the acute setting for HF patients. Radiological parameters (such as cortical thickness [ 34 , 35 ], Singh index, and Dorr classification [ 32 ]) were revealed to be associated with osteoporosis or mortality risks. Despite this, lots of BMD information from clinical CT imaging of HF has not been fully utilized.…”

Section: Discussionmentioning

confidence: 99%

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Association Between Hip Bone Mineral Density and Mortality Risk After Hip Fracture: A Prospective Cohort Study

Chen

et al. 2023

Calcif Tissue Int

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Factors related to mortality after osteoporotic hip fracture (HF) have been investigated intensively, except for proximal femoral bone mineral density (BMD), which is also the primary cause of osteoporosis. In this study, we aimed to investigate the association of hip BMD with mortality risk after HF. Four hundred and eleven elderly patients with HF in Beijing, China, were included and prospectively followed up with a median time of 3 years. At baseline, quantitative CT technique (QCT) was used to measure areal BMD (aBMD) of the unaffected hip. Areal BMDs of the total hip (TH), femoral neck (FN), trochanter (TR), and intertrochanter were analyzed with postoperative mortality as the primary outcome. A total of 394 patients (78.59 ± 7.59 years, 75.4% female) were included in our final analysis, with 86 (82.23 ± 7.00 years, 81.4% female) dead. All hip bone densities demonstrated a significant association with mortality risks in the unadjusted model, but only TR aBMD remained significantly correlated after adjusting for all covariates. Compared to the lower TR aBMD group, the higher TR aBMD group yielded significantly lower death risks (HR 0.21 95% CI 0.05–0.9, P = 0.036). Higher survival probabilities were observed for higher TH and TR aBMD in survival analysis (P < 0.001). Hip BMD, especially TR BMD assessed by QCT, is an independent risk factor for postoperative mortality following HF. QCT may present a promising avenue for opportunistic analysis in immobilized patients, providing valuable information for early detection and personalized interventions to enhance patient outcomes.

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