Is Renal Living-Donor Transplantation Indicated in Adult Patients with Orthotopic Ileal Neobladder? Lessons Learned from a Clinical Case

Airoldi, Andrea; Volpe, Alessandro; Billia, Michele; Marchioro, G.; Fenoglio, Roberta; Lazzarich, Elisa; Sacchetti, GianMario; Baiocco, Cinzia; Inglese, Eugenio; Menegotto, Alberto; Terrone, Carlo; Stratta, Piero

doi:10.1016/j.eururo.2009.05.020

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…For this reason, it was suggested that the urinary diversion types to be made should be discussed in detail with the patients, especially for the recipients who have living donors [18].…”

Section: Discussionmentioning

confidence: 99%

Radical Cystectomy and Ileal Conduit Diversion for Bladder Urothelial Carcinoma With Sarcomatoid and Squamous Variants After Renal Transplantation

Yavuzsan

Yeşildal

Kireççi

et al. 2020

Cureus

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Renal transplantation is the optimal treatment for patients with end-stage renal disease. However, the incidence of malignancies, especially urological malignancies, increases after renal transplantation due to long-term immunosuppressive treatments. We report a case of radical cystectomy and ileal conduit diversion in a 39-year-old female patient who developed invasive bladder carcinoma with extravesical extension three years after renal transplantation. Radical cystectomy and ileal conduit diversion surgery are feasible options for patients who developed invasive bladder cancer after renal transplantation and are effective methods for the protection of renal functions in the short-term follow-up period.

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“…For this reason, it was suggested that the urinary diversion types to be made should be discussed in detail with the patients, especially for the recipients who have living donors [18].…”

Section: Discussionmentioning

confidence: 99%

Radical Cystectomy and Ileal Conduit Diversion for Bladder Urothelial Carcinoma With Sarcomatoid and Squamous Variants After Renal Transplantation

Yavuzsan

Yeşildal

Kireççi

et al. 2020

Cureus

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“…This might explain the unfavourable case described by Airoldi et al. , who observed severe acidosis in a patient who had a Camey II neobladder for tuberculosis and subsequently received renal transplantation [22].…”

Section: Discussionmentioning

confidence: 99%

“…Other noncompletely detubularized ileal neobladders (such as Camey II) are presently less in favour even in normal cystectomy patients since they present a less optimal surface to volume ratio, therefore increasing the possibility of metabolic acidosis. This might explain the unfavourable case described by Airoldi et al, who observed severe acidosis in a patient who had a Camey II neobladder for tuberculosis and subsequently received renal transplantation [22].…”

Section: Neobladder In Renal Transplant Recipientsmentioning

confidence: 96%

Orthotopic bladder substitute in renal transplant recipients: experience with Studer technique and literature review

Manassero¹,

Paola²,

Mogorovich³

et al. 2011

Transplant International

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Summary Renal transplant recipients with high‐risk bladder cancer following cystectomy need a urinary diversion preserving the renal function and possibly maintaining body image, while still offering the best oncological outcome. The aim of this report is to describe our experience of radical cystectomy and orthotopic ileal neobladder with Studer technique in this population, and to review the literature. We performed radical cystectomy and Studer ileal neobladder in four male patients (median age 67 years) after median time of 9.5 years following renal transplantation. Pathology revealed pT1HGN+ transitional cell carcinoma in one case, pT1HGN0 in two and pT3aHGN0 in one. Two patients presenting aggressive disease (N+ and pT3a) died of tumour progression after 20 and 14 months, respectively, while the other two are alive after 56 and 36 months of follow‐up with no evidence of disease, stable serum creatinine (2.29 and 1.6 mg/dl) and mild metabolic acidosis. Day and night‐time urinary continence were satisfactory in all patients. Good functional outcomes have been reported in the 20 cases of ileal orthotopic neobladder with different techniques published so far and the global experience of 24 cases with a median follow‐up of 39 months documents a cancer specific survival of 62.5%.

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Bladder Tuberculosis

Kulchavenya

2014

Urogenital Tuberculosis: Epidemiology, Diagnosis, Therapy

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Is Renal Living-Donor Transplantation Indicated in Adult Patients with Orthotopic Ileal Neobladder? Lessons Learned from a Clinical Case

Cited by 5 publications

References 8 publications

Radical Cystectomy and Ileal Conduit Diversion for Bladder Urothelial Carcinoma With Sarcomatoid and Squamous Variants After Renal Transplantation

Radical Cystectomy and Ileal Conduit Diversion for Bladder Urothelial Carcinoma With Sarcomatoid and Squamous Variants After Renal Transplantation

Orthotopic bladder substitute in renal transplant recipients: experience with Studer technique and literature review

Bladder Tuberculosis

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