Is splenectomy for massive splenomegaly safe in children?

Al-Salem, Ahmed H.

doi:10.1016/s0002-9610(99)00118-x

Cited by 9 publications

(2 citation statements)

References 28 publications

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“…Hypersplenism increase the requirement for blood transfusion and hence increase the risk of hepatitis. So, early splenctomy (after 4 years and before 15 years) may decrease the chance of getting HCV infection by decreasing the need for blood transfusion, this is supported by study done by Al-Salem (43).…”

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confidence: 77%

Prevalence and risk factors for hepatitis C virus in Beta thalassemic patients attending blood diseases center in Ibn- AL -Baladi Hospital, Baghdad

Ali¹

2018

Al-Kindy Col. Med. J

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Background: Thalassemias are a group of heterogeneous genetic disorders, in which the rate of production of hemoglobin is partially or completely suppressed due to reduced rate of synthesis of α or β- chain Objectives: to estimate the prevalence of Hepatitis C infection among B thalassemia patients attending Ibn-AL-Baladi center of blood diseases in AL-Sader city, in AL-Resafa Quarter of Baghdad and to determine the possible risk factors. Type of the study: Cross- sectional study. Methods: A cross sectional study conducted on B Thalassemia patients attending the blood diseases center in Ibn-AL-Baladi hospital during the period from 1st of July till the 31st of December 2015. Results: All of 400 eligible patients, who were recruited to be included in this study, were accepted to participate in the study giving an overall response rate 100%. The prevalence rate of Hepatitis C according to anti HCV antibody test among the study group was 26%. Conclusions: we conclude that about quarter of Iraqi thalassemic patients visiting the thalassemia center in Ibn-AL-Baladi hospital have HCV infection

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confidence: 77%

Prevalence and risk factors for hepatitis C virus in Beta thalassemic patients attending blood diseases center in Ibn- AL -Baladi Hospital, Baghdad

Ali¹

2018

Al-Kindy Col. Med. J

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“…This is because many of Splenectomized patients are older than non-splenectomized patients (i.e., additional risk factor), and splenic-tomy done mostly in thalassemic patient because of hypersplenism which in turn increase the number of blood trans-fusion and the risk of hepatitis. So, early splenectomy (after 4 years and before 15 years) with good preoperative management can decrease the risk of hepatitis infection by decreasing the need for blood transfusion, with no significant increase in the rate of postoperative morbidity and mortality (33) . CONCLUSION 1-The percent of HCV among thalassemic patients in Holy Najaf is lower than previous Iraqi studies.…”

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confidence: 99%

Factors Affecting the Transmission epatitis C Among the Thalassemic Patients in Al-Najaf Al-Ashraf governorate

NASRAWI¹,

Musa²,

Atiyah³

et al. 2022

KMJ

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Background: Because thalassemic patients require multiple blood transfusions, and blood transfusion is a common transmission vector for hepatitis C virus, numerous studies have found varying prevalences of hepatitis C among -thalassemia major patients. As a result, this study was carried out to discover anti-HCV in thalassemia patients in our location. Objectives: to find factors that increase the chance of getting infection with HCV in thalassemia patients. Materials and methods: A total of 550 patients whose registered in thalassemic center were surveyed, 48 of them had HCV infection. Name, age, sex, residency, age at starting blood transfusion, Frequency of blood transfusion per month, Splenectomized or not, blood group for patients, test for HCV antibodies and liver function test. Results: The total number surveyed was 550, where the number of males was 330, while the number of females was 220. The study group comprised 48 thalassemic patients (33 [68.75%] males and 15 [31.25%] females). The mean ± SD age was 18.4 ± 7.57months (range: 2 – 35). There is direct association between the age and the seropositivity to anti –HCV where HCV seropositivity was significantly associated with an older age (P ≤ 0.01). There is no association between gender and seropositivity to anti –HCV where there are no significant differences (P= 0.653) Out of 48 patients 26(54.14%) were live in urban, 22(45.17%) in rural. In regard to residency there is no direct relationship (P ≤ 0.01) between the residency and the seropositivity to anti –HCV. There is high significant (P ≤ 0.01) between frequency of blood transfusion per month and seropositivity to anti –HCV. HCV seropositivity was significantly associated with the longer duration of the disease (P ≤ 0.01). Patients of O+ blood group represented the higher (P ≤ 0.01) seropositivity to anti -HCV than patients with other blood groups, however patients with Rh- shows lower seropositivity to anti -HCV. Our study shows that there is highly significant (P ≤ 0.01) relation between splenectomy and the seropositivity to anti –HCV.

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Thalassemia Major

Riccio

2014

Encyclopedia of Special Education

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Is splenectomy for massive splenomegaly safe in children?

Cited by 9 publications

References 28 publications

Prevalence and risk factors for hepatitis C virus in Beta thalassemic patients attending blood diseases center in Ibn- AL -Baladi Hospital, Baghdad

Prevalence and risk factors for hepatitis C virus in Beta thalassemic patients attending blood diseases center in Ibn- AL -Baladi Hospital, Baghdad

Factors Affecting the Transmission epatitis C Among the Thalassemic Patients in Al-Najaf Al-Ashraf governorate

Thalassemia Major

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