Is Stress Hyperglycemia a Predicting Factor of Developing Diabetes in Future?

Moradi, Sedighe; Keshavarzi, A.; Tabatabaee, Seyed Morteza

doi:10.1055/s-0035-1559719

Cited by 13 publications

(8 citation statements)

References 10 publications

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“…Informed consent was taken from each participant before the study. After taking blood samples and anthropometric measurements, 14 of them were excluded due to diabetes (FBS ≥126 mg/dL 29 in two occasions), leaving 164 people (82 men, 82 women) to conduct the research.…”

Section: Methodsmentioning

confidence: 99%

Association of endotoxaemia with serum free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case–control study in northwest of Iran

et al. 2017

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ObjectivesThis study aimed to compare serum free fatty acids (FFAs) and lipopolysaccharide-binding protein (LBP) between metabolically healthy abdominally obese (MHAO) and metabolically unhealthy abdominally obese (MUAO) individuals. We also examined the association between serum FFAs and LBP in the participants.MethodsIn this age-matched and gender-matched case–control study, 164 abdominally obese subjects were recruited from June to November 2015 in the northwest of Iran. Demographic data, dietary intake, body composition, anthropometric indices and physical activity (PA) were assessed. Basal blood samples were collected to determine serum metabolic parameters, FFAs and LBP. Abdominal obesity was defined as having waist circumference ≥95 cm. Those with three or more metabolic alterations were defined as MUAO and those having two or less were classified as MHAO. Data were analysed using SPSS V.17.0.ResultsThere were no significant differences in dietary intake, anthropometric indices, body composition and PA between the two groups. The odds of MUAO significantly increased by increments in serum fasting blood sugar (OR 3.79, 95% CI 2.25 to 6.40), triglycerides (OR 1.10, 95% CI 1.05 to 1.15), systolic blood pressure (OR 1.02, 95% CI 1.00 to 1.04) and diastolic blood pressure (OR 1.03, 95% CI 1.01 to 1.06) and decreased by increase in serum high-density lipoprotein cholesterol (OR 0.32, 95% CI 0.20 to 0.52). The levels of LBP and FFAs showed no significant differences between the two groups. However, significant correlations were found between LBP and FFAs in pooled population (r=0.712; p<0.001) as well as in cases (r=0.717; p<0.001) and controls (r=0.704; p<0.001). Neither FFAs nor LBP were significantly correlated with dietary intake or metabolic parameters (p>0.05).ConclusionThe results indicated that serum LBP and FFAs are highly correlated both in MHAO and MUAO states. In addition, the levels of LBP and FFAs seem to be more related to abdominal obesity than to the presence or absence of metabolic health.

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Section: Methodsmentioning

confidence: 99%

Association of endotoxaemia with serum free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case–control study in northwest of Iran

et al. 2017

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“…However, it is certainly not known whether surviving SHY1 patients are prone to future development of glucose metabolism derangement. Moradi et al [15] demonstrated a significant relationship between SHY1 and the development of diabetes mellitus (DM) among 98 adult patients referred to the emergency room due to trauma, myocardial infarction, subarachnoid hemorrhage, head trauma, sepsis, or abdominal surgery: 8% developed DM and 26% developed prediabetes.…”

Section: Shy1: Severe and Prolonged Illnessmentioning

confidence: 99%

Non-Diabetic Hyperglycemia in the Pediatric Age: Why, How, and When to Treat?

et al. 2018

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Purpose of review Non-diabetic hyperglycemia (NDHY) is a pathological condition that is not yet well known. The aim of this review is to examine approaches for management of this condition. Recent findings While it is well known that persistent hyperglycemia in diabetes affects immune response and risk for diabetesrelated micro-and macrovascular complications, little is known about the biological effects of transient NDHY, particularly in the pediatric age group. Summary Stress HY (SHY) is typically defined as blood glucose > 8.33 mmol/L (150 mg/dL) during physical stress, resolving spontaneously after dissipation of acute illness in patients without known diabetes. Based on the literature and clinical practice, two situations can be classified: (1) SHY1, which occurs during severe and prolonged illness and under serious life-threatening conditions, mainly in emergency situations and in resuscitation areas; and (2) SHY2, which occurs during acute illness, mainly in non-life-threatening conditions. Furthermore, (NDHY) among pediatric patients can be induced by drugs; the most frequent conditions are secondary to (1) steroid therapy and (2) antineoplastic/immunosuppressive therapy. Keywords Non-diabetic hyperglycemia . Stress hyperglycemia . Drug-induced hyperglycemia . Management This article is part of the Topical Collection on Pediatric Type 2 and Monogenic Diabetes * Enza Mozzillo

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“…Stress hyperglycemia is a transient increase in blood glucose during acute physiological stress in the absence of diabetes (normal glucose homeostasis before stress). This phenomenon usually will be determined in critically ill patients and the concentration of glucose varies in the range of 140-300 mg/dl [2].…”

Section: Introductionmentioning

confidence: 99%

Does stress hyperglycemia affect mortality? Acute myocardial infarction – case control study

Cinar

Avcı

Gülen

et al. 2019

Arch Med Sci Atheroscler Dis

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Introduction: We aimed to investigate the effect of stress (acute) hyperglycemia in patients with acute coronary syndrome who had not been previously diagnosed with diabetes mellitus (DM) on the prognosis of the disease in terms of mortality. Material and methods: Patients who were admitted to the Adana Numune Training and Research Hospital Emergency Service Clinic between August 2010 and August 2013 and whose plasma blood glucose level was over 140 mg/dl at the time of admission but were not previously diagnosed with DM, who were over the age of 18 and considered to have acute myocardial infarction were included. Results: A total of 259 patients whose data were fully attainable were included in the study. 80.3% (n = 208) of the patients were male and 19.7% (n = 41) were female. Non-ST elevation myocardial infarction was found in 71.6%, ST elevation myocardial infarction was found in 28.4% of the patients with stress hyperglycemia. It was determined that 10.1% of patients with stress-related hyperglycemia and 1.3% of patients without stress-related hyperglycemia had died. Conclusions: The plasma blood glucose level at presentation of patients diagnosed with acute myocardial infarction at the emergency room is associated with early in-hospital mortality.

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Is Stress Hyperglycemia a Predicting Factor of Developing Diabetes in Future?

Abstract: Our study demonstrates a significant relationship between stress hyperglycemia and development of diabetes. Stress hyperglycemia could be a predicting factor of development of diabetes.

Cited by 13 publications

References 10 publications

Association of endotoxaemia with serum free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case–control study in northwest of Iran

Association of endotoxaemia with serum free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case–control study in northwest of Iran

Non-Diabetic Hyperglycemia in the Pediatric Age: Why, How, and When to Treat?

Does stress hyperglycemia affect mortality? Acute myocardial infarction – case control study

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