Is tea tree oil an important contact allergen?

Veien, Niels K.; Rosner, Karli; Skovgaard, Gunhild Lange

doi:10.1111/j.0105-1873.2004.0350f.x

Cited by 41 publications

(28 citation statements)

References 7 publications

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“…A mean irritancy score of 0.25 has been found for neat TTO, based on patch testing results for 311 volunteers (10). Another study, in which 217 patients from a dermatology clinic were patch tested with 10% TTO, found no irritant reactions (150). Since irritant reactions may frequently be avoided through the use of lower concentrations of the irritant, this bolsters the case for discouraging the use of neat oil and promoting the use of well-formulated products.…”

Section: Dermal Toxicitymentioning

confidence: 99%

Melaleuca alternifolia(Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

2006

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SUMMARY Complementary and alternative medicines such as tea tree (melaleuca) oil have become increasingly popular in recent decades. This essential oil has been used for almost 100 years in Australia but is now available worldwide both as neat oil and as an active component in an array of products. The primary uses of tea tree oil have historically capitalized on the antiseptic and anti-inflammatory actions of the oil. This review summarizes recent developments in our understanding of the antimicrobial and anti-inflammatory activities of the oil and its components, as well as clinical efficacy. Specific mechanisms of antimicrobial and anti-inflammatory action are reviewed, and the toxicity of the oil is briefly discussed.

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Section: Dermal Toxicitymentioning

confidence: 99%

Melaleuca alternifolia(Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

2006

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“…Some essential oils have the potential to be toxic (Prashar et al, 2004;Hayes and Markovic, 2003), while others initiate allergic reactions when applied to the skin via massage (Veien et al, 2004;Schnuch et al, 2004;Crawford et al, 2004;MaddocksJennings, 2004;Scardamaglia et al, 2003;Mozelsio et al, 2003;Bleasel et al, 2002;Vilaplana and Romaguera, 2002;Romaguera and Vilaplana, 2000). These allergic reactions arise from certain constituents, e.g.…”

Section: Massagementioning

confidence: 99%

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

Edris

2007

Phytotherapy Research

1,095

688

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Essential oils and their volatile constituents are used widely to prevent and treat human disease. The possible role and mode of action of these natural products is discussed with regard to the prevention and treatment of cancer, cardiovascular diseases including atherosclerosis and thrombosis, as well as their bioactivity as antibacterial, antiviral, antioxidants and antidiabetic agents. Their application as natural skin penetration enhancers for transdermal drug delivery and the therapeutic properties of essential oils in aroma and massage therapy will also be outlined.

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“…Centred on a patch test study of 311 volunteers, it was determined that neat 5% tea tree oil can cause irritancy (mean irritancy score of 0.25) [362]. In contrast, however, the study of 217 patients from a dermatology clinic, subjected to a patch test with 10% M. alternifolia oil, showed no irritation [363]. Two additional studies tested the M. alternifolia in patch tests at concentrations of 5% and 10%; 0.15–1.8% of patients experienced allergic contact dermatitis [364, 365].…”

Section: Essential Oil Toxicitymentioning

confidence: 99%

Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases

Orchard

Vuuren

2017

Evidence-Based Complementary and Alternative Medicine

183

121

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Essential oils are one of the most notorious natural products used for medical purposes. Combined with their popular use in dermatology, their availability, and the development of antimicrobial resistance, commercial essential oils are often an option for therapy. At least 90 essential oils can be identified as being recommended for dermatological use, with at least 1500 combinations. This review explores the fundamental knowledge available on the antimicrobial properties against pathogens responsible for dermatological infections and compares the scientific evidence to what is recommended for use in common layman's literature. Also included is a review of combinations with other essential oils and antimicrobials. The minimum inhibitory concentration dilution method is the preferred means of determining antimicrobial activity. While dermatological skin pathogens such as Staphylococcus aureus have been well studied, other pathogens such as Streptococcus pyogenes, Propionibacterium acnes, Haemophilus influenzae, and Brevibacterium species have been sorely neglected. Combination studies incorporating oil blends, as well as interactions with conventional antimicrobials, have shown that mostly synergy is reported. Very few viral studies of relevance to the skin have been made. Encouragement is made for further research into essential oil combinations with other essential oils, antimicrobials, and carrier oils.

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Is tea tree oil an important contact allergen?

Cited by 41 publications

References 7 publications

Melaleuca alternifolia(Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

Melaleuca alternifolia(Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases

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