Is the Presence of a Solitary Kidney an Independent Risk Factor for Acute Kidney Injury after Contrast-enhanced CT?

McDonald, Jennifer S.; Katzberg, Richard W.; McDonald, Robert J.; Williamson, Eric E.; Kallmes, David F.

doi:10.1148/radiol.2015142676

Cited by 17 publications

(16 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of interest are the data on the demographics of their SFK cohort, which shows hypertension in 65% and CKD in 39%. This was significantly higher than the control cohort with 47% and 10%, respectively [ 80 ], highlighting the potential health issues in any individual with an SFK.…”

Section: Adult Lifementioning

confidence: 96%

See 1 more Smart Citation

Life with one kidney

Schreuder¹

2017

Pediatr Nephrol

View full text Add to dashboard Cite

Life with a solitary functioning kidney (SFK) may be different from that when born with two kidneys. Based on the hyperfiltration hypothesis, a SFK may lead to glomerular damage with hypertension, albuminuria and progression towards end-stage renal disease. As the prognosis of kidney donors was considered to be very good, having a SFK has been considered to be a benign condition. In contrast, our research group has demonstrated that being born with or acquiring a SFK in childhood results in renal injury before adulthood in over 50% of those affected. Most congenital cases will be detected during antenatal ultrasound screening, but up to 38% of cases of unilateral renal agenesis are missed. In about 25–50% of cases of antenatally detected SFK there will be signs of hypertrophy, which could indicate additional nephron formation and is associated with a somewhat reduced risk of renal injury. Additional renal and extrarenal anomalies are frequently detected and may denote a genetic cause for the SFK, even though for the majority of cases no explanation can (yet) be found. The ongoing glomerular hyperfiltration results in renal injury, for which early markers are lacking. Individuals with SFK should avoid obesity and excessive salt intake to limit additional hyperfiltration. As conditions like hypertension, albuminuria and a mildly reduced glomerular filtration rate generally do not result in specific complaints but may pose a threat to long-term health, screening for renal injury in any individual with a SFK would appear to be imperative, starting from infancy. With early treatment, secondary consequences may be diminished, thereby providing the optimal life for anyone born with a SFK.

show abstract

Section: Adult Lifementioning

confidence: 96%

“…McDonald et al studied the risk of contrast-induced acute kidney injury in a cohort of 264 SFK patients, of whom at least 80% had a nephrectomy in adulthood [ 80 ]. Their analysis of the risk with a propensity score-matched control group did not show an increased risk of acute kidney injury in the SFK cohort.…”

Section: Adult Lifementioning

confidence: 99%

Life with one kidney

Schreuder¹

2017

Pediatr Nephrol

View full text Add to dashboard Cite

show abstract

“…Are Patients with a Single Kidney at Increased Risk for CA-AKI or CI-AKI Beyond That Associated with Their eGFR? Patients with a single normal or partially functioning kidney (eg, kidney agenesis, nephrectomy, transplant) should be managed similarly to patients with normal kidney volume (eg, two normal kidneys) (15,48). In patients with a single normal or partially functioning kidney, clinical risk should be determined based on overall kidney function (ie, eGFR) and clinical circumstances (ie, AKI).…”

Section: Do Patients Undergoing Maintenance Dialysis With Residual Kimentioning

confidence: 99%

“…In patients with a single normal or partially functioning kidney, clinical risk should be determined based on overall kidney function (ie, eGFR) and clinical circumstances (ie, AKI). The presence of a solitary functioning kidney should not influence decision making regarding the risk of CA-AKI or CI-AKI (15,48).…”

Section: Do Patients Undergoing Maintenance Dialysis With Residual Kimentioning

confidence: 99%

Use of Intravenous Iodinated Contrast Media in Patients with Kidney Disease: Consensus Statements from the American College of Radiology and the National Kidney Foundation

et al. 2020

Self Cite

View full text Add to dashboard Cite

“…McDonald et al retrospectively examined 6,175 patients who received contrast-enhanced CT in a single facility. 68 Propensity score (1:3) matching was performed to adjust for basal renal function and underlying diseases, and 247 patients with solitary kidney and 691 patients with bilateral kidneys were compared. Enhanced CT was performed 30 days after nephrectomy (76% due to malignant tumor; 5% in transplant recipients; 19% in others).…”

Section: Level Of Evidence: Iva / Grade Of Recommendation: B (Minds 2mentioning

confidence: 99%

Guideline on the Use of Iodinated Contrast Media in Patients With Kidney Disease 2018

Isaka

Hayashi

Aonuma

et al. 2019

Circ J

View full text Add to dashboard Cite

2574 ISAKA Y et al. administered and whether measures to prevent CIN are necessary. Any use of contrast media that is not consistent with the revised guideline reflects the decisions made by the attending physicians on the basis of conditions specific to their patients, and their decisions should be prioritized. The present guideline does not provide any legal basis for prosecuting physicians who do not use contrast media according to the guideline. ▋ 1.3 Selection of Literature, Levels of Evidence, and Grades of Recommendations The revised guideline was prepared according to the procedures proposed by Minds. The guideline writing committee discussed and revised CQs on 9 themes regarding CIN. The working groups addressed the CQs by critically reviewing literature published from September 1, 2011 to March 31, 2017 in major literature databases (e.g., PubMed, MEDLINE, the Cochrane Library, and the Japan Centra Revuo Medicina [Ichushi]), in addition to the literature referenced in the CIN guideline 2012. Literature published since April 2017 was also included as deemed necessary by the guideline committee. Since the CIN guideline 2012 was prepared according to the Minds guideline 2007, CQs included in 2012 were revised according to the Minds guideline 2007. New CQs added in this revised guideline, CQ3-12, CQ5-6, CQ5-7, and CQ6-4, were prepared according to "Minds Guidebook for Guideline Development 2014" and "Minds Manual for Guideline Development 2017". Thus, in this revised guideline, 2 kinds of evidence and recommendation evaluation methods were adopted. A level of evidence and grade of recommendation were assigned to the answers to the CQs.

show abstract

Is the Presence of a Solitary Kidney an Independent Risk Factor for Acute Kidney Injury after Contrast-enhanced CT?

Abstract: Our study did not demonstrate any significant differences in the rate of AKI, dialysis, or death attributable to contrast-enhanced CT in patients with a solitary kidney versus bilateral kidneys.

Cited by 17 publications

References 21 publications

Life with one kidney

Life with one kidney

Use of Intravenous Iodinated Contrast Media in Patients with Kidney Disease: Consensus Statements from the American College of Radiology and the National Kidney Foundation

Guideline on the Use of Iodinated Contrast Media in Patients With Kidney Disease 2018

Contact Info

Product

Resources

About