Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings : cardiovascular topic

Parsa, Amir Farhang Zand; Jahanshahi, Bahareh

doi:10.5830/cvja-2014-054

Cited by 27 publications

(26 citation statements)

References 21 publications

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“…Thus the WHR was found to be more strong predictor of the severity of CAD. This result was comparable with the study of Parsa and Jahanshahi 21 .…”

supporting

confidence: 91%

“…The mean WHR was found 0.96±0.07 and 0.88±0.05 in moderate to severe and normal to mild CAD respectively and was statistically significant (p=<0.001). Similar finding was evaluated by Parsa and Jahanshahi 21 .…”

supporting

confidence: 89%

“…It also has the advantage that even minor atherosclerotic lesions at a subclinical stage can be detected and may become a target for preventive and therapeutic interventions 16 . Several studies also demonstrated that WHR had strong relation with angiographic severity CAD both in men and women [16][17][18][19][20][21] This cross sectional observational study was carried out among 105 patients with acute STEMI who received thrombolytic and underwent CAG at NICVD, Dhaka from May, 2016 to November, 2016. Acute STEMI patients who were not thrombolysed, not subjected to do CAG, with previous H/O percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG), systemic infection and non-cardiovascular diseases (like hepatic dysfunction, CKD, malignancy) and who had participated in weightreducing programs (including diets) or received related medications were excluded from the study.…”

Section: Association Of Waist-hip Ratio With Angiographic Severity Ofmentioning

confidence: 99%

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Association of Waist-Hip Ratio with Angiographic Severity of Coronary Artery Disease in Patients with Acute ST- Segment Elevation Myocardial Infarction

Akanda

Ullah²,

Barai

et al. 2018

Bangladesh Heart J

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Objective: Coronary artery disease (CAD) is rising in South Asia and is taking a more malignant proportion in South Asians than in Caucasians. Having a similar socioeconomic and cultural background, the scenario is same in Bangladesh. Obesity, especially abdominal is concerned as an important and modifiable risk factor for CAD which is now also raising both in developed and under developed countries. Waist-Hip ratio (WHR) is considered as an important tool for assessing abdominal obesity. The aim of this study is to evaluate the association between WHR and the severity of CAD of acute ST-segment elevation myocardial infarction (STEMI) patients so that primary prevention, early detection and proper management strategy can be taken to reduce the disease burden, morbidity and mortality.Methods: This cross sectional observational study was carried out among 105 patients with acute STEMI who received thrombolytic and underwent coronary angiography (CAG) at National Institute of Cardiovascular Diseases (NICVD), Dhaka from May, 2016 to November, 2016. They were divided into two groups, Group I (normal WHR) = 51 and group II (increased WHR) = 54, according to WHR level. Angiographic severity of coronary artery disease was assessed by vessel score and Genseni’s score.Results: Significant positive correlation was found between WHR and vessel score (r= 0.62, p=0.003). Moderate to severe CAD patients were significantly higher in increased WHR group than in normal WHR group (77.8% vs. 29.4%, p=<0.001). Significant positive correlation was also found between WHR and Genseni’s score (r= 0.71, p=0.001). Logistic regression analysis showed that a patient with increased WHR had 2.75 times higher risk of having significant CAD compared with those with the normal WHR.Conclusions: Increased WHR group had more significant coronary artery disease in terms of vessel score and Genseni’s score and can be considered as a predictor of the severity of the CAD disease in acute STEMI patients.Bangladesh Heart Journal 2017; 32(2) : 70-76

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“…Thus the WHR was found to be more strong predictor of the severity of CAD. This result was comparable with the study of Parsa and Jahanshahi 21 .…”

supporting

confidence: 91%

supporting

confidence: 89%

Section: Association Of Waist-hip Ratio With Angiographic Severity Ofmentioning

confidence: 99%

See 1 more Smart Citation

Association of Waist-Hip Ratio with Angiographic Severity of Coronary Artery Disease in Patients with Acute ST- Segment Elevation Myocardial Infarction

Akanda

Ullah²,

Barai

et al. 2018

Bangladesh Heart J

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“…Previous studies have suggested obesity as a protective factor for CAD, the so-called obesity paradox. 14 Nevertheless, such paradox is not concerned to abdominal obesity, which has been associated with CAD and considered more pathological than subcutaneous fat accumulation. 14 - 16 In our study, we did not measure abdominal circumference, which may have influenced the consistency of results.…”

Section: Discussionmentioning

confidence: 99%

Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography

Gabriel¹,

Gonçalves²,

Melo³

et al. 2018

Arquivos Brasileiros De Cardiologia

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BackgroundIn view of the high mortality for cardiovascular diseases, it has become necessary to stratify the main risk factors and to choose the correct diagnostic modality. Studies have demonstrated that a zero calcium score (CS) is characteristic of a low risk for cardiovascular events. However, the prevalence of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized literature.ObjectiveTo evaluate the frequency of patients with coronary atherosclerotic plaques, their degree of obstruction and associated factors in patients with zero CS and indication for coronary computed tomography angiography (CCTA).MethodsThis is a cross-sectional, prospective study with 367 volunteers with zero CS at CCTA in four diagnostic imaging centers in the period from 2011 to 2016. A significance level of 5% and 95% confidence interval were adopted.ResultsThe frequency of atherosclerotic plaque in the coronary arteries in 367 patients with zero CS was 9.3% (34 individuals). In this subgroup, mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), with involvement of two or more segments in 4 (25%) patients. The frequency of non-obese individuals (90.6% vs 73.9%, p = 0.037) and alcohol drinkers (55.9% vs 34.8%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, with an odds ratio of 3.4 for each of this variable.ConclusionsThe frequency of atherosclerotic plaque with zero CS was relatively high, indicating that the absence of calcification does not exclude the presence of plaques, many of which obstructive, especially in non-obese subjects and alcohol drinkers.

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“…In another study Parsa and Jahanshahi. 16 found the prevalence of cigarette smoking, HTN, DM, hyperlipidemia, and family history of CAD were 45.8%, 39.1%, 27.3%, 29.5%, and 26.3% respectively. These differences might be due to variation in the life style, degree of motivation and level of education.…”

Section: Discussionmentioning

confidence: 89%

In-Hospital Outcomes of Acute ST Elevation Myocardial Infarction in Patients with Acute Kidney Injury

Haque¹,

Ali

Aziz

et al. 2018

Cardiovasc. j.

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Background: Acute kidney injury (AKI) is a risk factor for long-term adverse outcomes, including acute myocardial infarction and death. The objective of this study was to find out in-hospital outcomes in patients with acute ST elevation myocardial infarction with acute kidney injury.Methods: A total 190 patients were included in this study and were equally divided into two groups, Group-I (with AKI) and Group-II (without AKI), according to absolute changes of serum creatinine level. AKI was defined as absolute changes in serum creatinine (SCr. at 48 hours’ minus admission SCr) and categorized as mild AKI (increase of 0.3 to <0.5 mg/d), moderate AKI (increase of 0.5 to <1.0 mg/dl), and severe AKI (increase of e”1.0 mg/dl) using Acute Kidney Injury Network (AKIN) criteria.Results: Overall in-hospital mortality rate was 14.7% in Group-I (mortality rate for those with mild, moderate, and severe AKI were 7%, 13.3%, and 31.8%) compared with 5.3% in Group-II. Regarding inhospital morbidities, significant arrhythmia (29.5%) was the most common complication followed by acute heart failure (18.9%), cardiogenic shock (12.6%), and mechanical complications (4.2%) which were more in Group-I compared to patients with Group-II. After adjustment of other risk variables, the multivariate logistic regression analysis revealed AKI remained an independent predictor of in-hospital mortality with adjusted odds ratios (OR) was 4.991 (95% confidence interval, 1.873-13.301).Conclusions: AKI is an independent predictor of in-hospital mortality and morbidity. It emphasizes the importance of efforts to identify risk factors and to prevent AKI during in-hospital management of acute STEMI patients.Cardiovasc. j. 2018; 11(1): 59-66

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Is the relationship of body mass index to severity of coronary artery disease different from that of waist-to-hip ratio and severity of coronary artery disease? Paradoxical findings : cardiovascular topic

Cited by 27 publications

References 21 publications

Association of Waist-Hip Ratio with Angiographic Severity of Coronary Artery Disease in Patients with Acute ST- Segment Elevation Myocardial Infarction

Association of Waist-Hip Ratio with Angiographic Severity of Coronary Artery Disease in Patients with Acute ST- Segment Elevation Myocardial Infarction

Atherosclerotic Plaque in Patients with Zero Calcium Score at Coronary Computed Tomography Angiography

In-Hospital Outcomes of Acute ST Elevation Myocardial Infarction in Patients with Acute Kidney Injury

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