Is the time from the onset to the treatment a prognostic indicator for hearing recovery in idiopathic sudden sensorineural hearing loss?

Uysal, İsmail Önder; Müderris, Togay; Polat, Kerem; Yüce, Salim; Gültürk, Sefa

doi:10.5606/kbbihtisas.2015.53138

Cited by 4 publications

(3 citation statements)

References 17 publications

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“…Chung et al performed a multivariate analysis of the prognostic factors of SSNHL and found that early treatment was associated with a good prognosis ( 6 ). Our study found that treatment onset time was an independent risk factor affecting the prognosis of SSNHL with the profound audiogram pattern, consistent with previous studies ( 2 , 9 , 27 ). This may be related to the microcirculation disorder of the inner ear.…”

Section: Discussionsupporting

confidence: 93%

Clinical features and prognostic factors of children with profound sudden sensorineural hearing loss

Ling

Su²,

Liang³

et al. 2022

Front. Pediatr.

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ObjectiveTo investigate the clinical features and factors affecting the prognosis of children with profound sudden sensorineural hearing loss (SSNHL).MethodsWe retrospectively analyzed the clinical data of 147 children with profound SSNHL who received inpatient treatment at our department from January 2016 to January 2021. All children were administered with systemic steroid therapy and/or intratympanic steroid (ITS) treatment for 2 weeks. Statistical analyses were performed for the clinical features, treatment effectiveness, and factors affecting the prognosis using SPSS 23.0.ResultsThe median age of the study population was 8 (6–10) years. The median treatment onset time was 8 (4–20) days. The most common concomitant symptom was tinnitus (45.58%). Laboratory findings showed that the percentages of children with abnormal leukocytes was 25.85%, abnormal platelet counts was 17.01%, abnormal cytomegalovirus IgG antibodies was 36.73% and abnormal Epstein–Barr (EB) virus IgG antibodies was 41.50%. The overall recovery rate of the treatment was 20.04%. The univariate analysis showed that age, treatment onset time, tinnitus, and ITS treatment were associated with the prognosis (p < 0.05). Regarding laboratory findings, the neutrophil count, lymphocyte count, and neutrophil-to-lymphocyte ratio differed significantly between the effective and invalid treatment effect groups (p < 0.05). The multivariable logistic regression analysis showed that treatment onset time [odds ratio (OR) = 0.936, 95% confidence interval (CI): 0.881–0.994] and ITS treatment (OR = 0.174, 95% CI: 0.044–0.0687) correlated with hearing recovery (p < 0.05).ConclusionIn this study, the earlier the treatment start time of children with profound SSNHL, the better was the prognosis. Further, ITS could be an effective treatment option.

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Section: Discussionsupporting

confidence: 93%

Clinical features and prognostic factors of children with profound sudden sensorineural hearing loss

Ling

Su²,

Liang³

et al. 2022

Front. Pediatr.

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“… 16 Uysal et al studied 96 ISHL patients and reported better recovery rates when the treatment began within the first week. 17 Similarly, Cho et al found significantly higher recovery rates (88%) in patients who were treated within the first 3 days. 18 Contradicting results are also present in the literature.…”

Section: Discussionmentioning

confidence: 90%

The Effects of Prognostic Factors in Idiopathic Sudden Hearing Loss

Bulğurcu

Şahin

Akgül³

et al. 2017

Int Arch Otorhinolaryngol

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Introduction Sudden hearing loss is one of the otologic emergencies. The treatment of this disease is affected negatively by some prognostic factors. Objective In this study, the effects of early treatment initiation in patients with idiopathic sudden hearing loss and of prognostic factors in early treated patients were investigated. Methods Out of the 216 patients admitted between September 2007 and September 2015, 154 were identified as having idiopathic sudden hearing loss; they were followed-up for a mean time of 7.4 months, and evaluated retrospectively. The effects of several parameters on the success of the treatment were statistically evaluated, such as the time the treatment was initiated, being of the female gender, the severity of the hearing loss, having descending type audiogram patterns, being older than 60 years old, and the co-presence of vertigo. Results Success rates were found to be significantly higher in idiopathic hearing loss patients that were admitted within the first week ( p < 0.05) of the onset of the hearing loss. However, the outcomes were found to be similar when patients admitted within the first 3 days and 4–7 days after the occurrence of the hearing loss were compared ( p > 0.05). Parameters such as female gender, severe hearing loss, descending type audiogram, being older than 60 years old, and co-presence of vertigo didn't reveal statistically significant effects on the outcome ( p >0.05). Conclusion The aforementioned prognostic factors, which are well-known in the literature, did not have significant effects when the idiopathic sudden hearing loss treatment was initiated within the first 7 days of the onset of the hearing loss.

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“…6,7) 현재까지 알려진 성인 돌발성 난청의 예후에 미치는 인자 는 청력저하 발생 후 치료까지 걸린 시간, 동반증상 유무, 기저 질환 유무, 초기 청력 저하 정도 등으로 알려져 있다. 8) 성인의 돌발성 난청과 달리 소아 돌발성 난청은 빈도가 적 고 예후가 불량한 것으로 여겨지며, 특히 10세 이하에서는 10 세 초과의 소아에 비해 더욱 치료결과가 나쁘다는 보고가 있 다. 9,10)…”

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Clinical Characteristics and Hearing Results of Sudden Sensorineural Hearing Loss in Child

Shin

Jung

Sung

et al. 2016

Korean J Otorhinolaryngol-Head Neck Surg

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Background and ObjectivesZZSudden sensorineural hearing loss (SSNHL) in children can occur just as can in adults; in fact, it may last throughout the entire life of a child, affecting the individual much more than when it does to an adult. As there are only a few studies that have focused on SSNHL in childhood, we investigated the clinical characteristics and hearing outcomes of pediatric SSNHL. Subjects and MethodZZA retrospective review of patients from November 2005 to May 2014 was carried out. Thirty nine patients under the age 15, who were hospitalized due to SSNHL were enrolled. Of these patients, 226 patients over the age of 15 were collected as a comparison group. Age, sex, underlying disease, site of hearing loss and duration from the onset to treatment were analyzed. We evaluated the overall recovery rate as well as the recovery rate according to accompanying diseases. ResultsZZRecovery rates were comparable between the pediatric and the adult group. Overall recovery rate was 60% in the pediatric group. Unlike for the adult group, dizziness and tinnitus were not a prognostic factor in the pediatric group. Pediatric patients showed similar overall recovery, whether the treatment initiation was under 7 days or more. Recurrence was seen in 3 patients, of which 2 showed complete recovery. ConclusionZZThe recovery rate for SSNHL was similar for the pediatric and the adult groups. A higher recurrence rate may alert clinicians to be aware of hearing changes after the recovery in pediatric patients.

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Is the time from the onset to the treatment a prognostic indicator for hearing recovery in idiopathic sudden sensorineural hearing loss?

Abstract: Our study results suggest that treatment outcomes are better in the patients presenting to hospital at an early stage of loss of hearing.

Cited by 4 publications

References 17 publications

Clinical features and prognostic factors of children with profound sudden sensorineural hearing loss

Clinical features and prognostic factors of children with profound sudden sensorineural hearing loss

The Effects of Prognostic Factors in Idiopathic Sudden Hearing Loss

Clinical Characteristics and Hearing Results of Sudden Sensorineural Hearing Loss in Child

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