Is There a Better Way to Biopsy the Prostate? Prospects for a Novel Transrectal Systematic Biopsy Approach

Andriole, Gerald L.; Bullock, Travis L.; Belani, Jay S.; Traxel, Erica; Yan, Yan; Bostwick, David G.; Humphrey, Peter A.

doi:10.1016/j.urology.2007.06.1128

Cited by 49 publications

(23 citation statements)

References 20 publications

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“…Electronic doppler ultrasound probes are becoming increasingly complex and sensitive to detect blood flow signals in the prostate to help guiding biopsy. TargetScan's device ultrasound probe is sector and at present can not be used for image-guided approaches, but seems to provide relatively reliable results regarding prostate mapping, which is very important for all targeted therapy approaches (Andriole et al, 2007). "Robotic" probes (ultrasound systems, which are just inserted into rectum by physician and then guided by pressing buttons, are being developed also by other manufacturers.…”

Section: Free Hand Systematic Biopsy Targeted Biopsy Prostatic Mappmentioning

confidence: 99%

Future of Prostate Biopsy: Who Will Get It and How?

Hajdinjak¹

2011

Prostate Cancer - Diagnostic and Therapeutic Advances

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Section: Free Hand Systematic Biopsy Targeted Biopsy Prostatic Mappmentioning

confidence: 99%

Future of Prostate Biopsy: Who Will Get It and How?

Hajdinjak¹

2011

Prostate Cancer - Diagnostic and Therapeutic Advances

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“…18,[21][22][23][24] The spectrum of prostate biopsy cores taken ranges from 6 to 80þ, yet it is not known how many cores are …”

Section: Patient Selectionmentioning

confidence: 99%

“…sufficient to assure that a clinically significant cancer will not be missed on the untreated side, 21,22,[24][25][26][27] Even a single positive core that is identified in low-risk PCa when obtained with routine transrectal biopsy techniques may not exclude bilateral disease in all instances. Barber and associates 28 investigated the data of 129 men with a single positive PCa core (in a 6-12 core biopsy), with 46 (36%) patients subsequently treated with RP.…”

mentioning

confidence: 99%

Contemporary Results of Focal Therapy for Prostate Cancer Using Cryoablation

Mouraviev

Johansen

Polascik

2010

Journal of Endourology

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The concept of focal therapy is rapidly evolving and gaining popularity from both physician and patient perspectives. We review the rationale, candidate selection, and results of the first clinical studies of focal cryoablation for selected patients with low volume and low-to low-moderate-risk features of prostate cancer as an alternative to whole-gland treatment. In spite of improved understanding of the tumor biology of early stage disease, we currently have limited tools to select appropriate patients with low-to low-moderate risk unifocal or unilateral prostate cancer who may be amenable to focal therapy. From a technical point, a number of ablative treatment options for focal therapy are available, with cryoablation having the most clinical experience. Recently, several reports have been published from single and multi-institutional studies that discuss focal therapy as a reasonable balance between cancer control and quality-of-life outcomes. Retrospective pathologic data from large prostatectomy series, however, do not clearly reveal valid and reproducible criteria to select appropriate candidates for focal cryoablation because of the complexity of tumorigenesis in early stage disease. At this time, a more feasible option remains hemiablation of the prostate with reasonable certainty about the absence of clinically significant cancer lesion(s) on the contralateral side of the prostate based on three-dimensional transperineal prostate biopsy mapping studies. Minimally invasive, parenchyma-preserving cryoablation can be considered as a potential feasible option in the treatment armamentarium of early stage, localized prostate cancer in appropriately selected candidates. There is a need to further test this technique in randomized, multicenter clinical trials.

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“…One of the common tissue extraction methods is needle biopsy. A recent study has shown that a Target Scan biopsy method has better accuracy over conventional practice to locate the malignant tissues (Andriole, 2007). Combined examination of PSA, DRE, and pathological tests provides a better diagnostic ability for prostate cancer (Partin, 1997).…”

Section: Introductionmentioning

confidence: 99%