Is there a correlation between the second to fourth digit ratio and vitiligo? A cross‐sectional study

Abstract

Vitiligo is a chronic skin disease that manifests itself as completely amelanotic, white, macules, and patches on any part of the body. Selective melanocyte apoptosis may result in irregular, progressive depigmented patches on the skin, mucosal membranes, and hair. Vitiligo is the most common cause of depigmentation on a global scale, with a prevalence of between 0.1% and 2% [1][2][3][4] .Vitiligo is a multifactorial, multigenic disease with complicated pathophysiology, including hereditary and non-genetic causes.Autoimmune, cytotoxic, oxidant-antioxidant, and neurological processes are implicated in melanocyte loss theories 5 . Although segmental and non-segmental vitiligo was formerly assumed to have independent etiologies, it has recently been shown that comparable inflammatory pathways may play a part in developing both forms 6 . Studies on sex hormones that may have a role in neuroendocrinological pathogenesis have been conducted. In their study, Hussein et al. discovered that male patients with adult vitiligo had