Is There a Relationship between Mean Blood Glucose and Glycated Hemoglobin?

Makris, Konstantinos; Spanou, Loukia

doi:10.1177/193229681100500634

Cited by 84 publications

(67 citation statements)

References 117 publications

(133 reference statements)

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“…However, HbA1c which is closely correlated with mean blood glucose [22], is not greatly affected by glycemic lability, e.g., changes in glucose concentration in a short time [22,48].…”

mentioning

confidence: 99%

Spironolactone and glucose metabolism, a systematic review and meta-analysis of randomized controlled trials

Zhao

Lin

et al. 2016

Journal of the American Society of Hypertension

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“…However, HbA1c which is closely correlated with mean blood glucose [22], is not greatly affected by glycemic lability, e.g., changes in glucose concentration in a short time [22,48].…”

mentioning

confidence: 99%

Spironolactone and glucose metabolism, a systematic review and meta-analysis of randomized controlled trials

Zhao

Lin

et al. 2016

Journal of the American Society of Hypertension

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“…HbA1c assay is not suitable to assess the glycemic control in diabetic pregnant women, with short red blood cells (RBCs) lifespan [34]. Vitamins C and E have been reported to lower HbA1c measurements, possibly by inhibiting glycation.…”

Section: Negative Outcomementioning

confidence: 99%

Serum Fructosamine and Glycosylated Hemoglobin in Monitoring the Glycemic Control in Gestational Diabetes Mellitus

Farghali¹,

Mahmoud²,

Baidas³

et al. 2018

OJOG

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Background: Diabetes mellitus complicates 1% -2% of all pregnancies, and associates with high perinatal morbidity. Gestational diabetes mellitus (GDM) is treatable condition, and women who have adequate glycemic control during pregnancy can effectively decrease the adverse outcomes of GDM. Objectives: This study was designed to compare the serum fructosamine, and the glycosylated hemoglobin (HbA1c), in monitoring the glycemic control in GDM. Patients and Methods: 1516 women with GDM included, and were advised for dietary modification to achieve proper glycemic control. If the target glucose levels were not reached by the diet regimen or by the dietary modification, insulin was prescribed for the studied women. The average values of the pre-and post-prandial glucose levels were calculated, and the insulin doses were adjusted to achieve the target glucose values during the antenatal visits. HbA1c, and fructosamine were measured to assess the glycemic control for the studied women. Results: The fructosamine, and the HbA1c were significantly high in the uncontrolled GDM compared to controlled group, and there was positive significant correlation between fractuosamine, and HbA1c in monitoring the glycemic control in GDM (r = 0.93, and P = 0.001). The

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“…Its relevance to diabetes management is that this blood test used to determine how well diabetes is being controlled (ADA, 2013). In short, hemoglobin A1c provides an average of level blood glucose control over the last 3 months (Makris & Spanou, 2011). Optimally it is used in combination with home blood glucose self-monitoring to make modifications in diabetes medicines.…”

Section: Implications For Practicementioning

confidence: 99%

The Synergistic Effects of HIV, Diabetes, and Aging on Cognition

Vance

Fazeli

Dodson

et al. 2014

Journal of Neuroscience Nursing

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In addition to the obvious health problems and/or physical limitations associated with HIV, diabetes, and aging, each of these are known to independently affect cognitive functioning. While this relationship to cognition does not necessarily mean frank cognitive impairments are inevitable with HIV, diabetes, and aging, it does entail that each of these conditions may lead to poorer cognitive performance compared to younger adults and individuals without HIV and diabetes. Many individuals may be aware of the physical symptoms associated with these diseases, but may be unaware of the cognitive outcomes associated with HIV and diabetes, especially if not controlled by medication and a healthy lifestyle. Additionally, individuals may be unaware of the significance of maintaining optimal cognitive functioning in order to maintain optimal everyday functioning abilities such as driving, cooking, managing medication regimens, and negotiating finances. Given that highly active antiretroviral therapy (HAART) has allowed individuals with HIV to live to reach older adulthood, and that dysglycemia and/or type 2 diabetes can be a metabolic side effect of these medications (Biron et al., 2012; Norbiato, 2012; Raper, 2010), it is reasonable to assume that there is a subset of individuals aging with HIV and diabetes, which may become more prevalent as individuals continue to age with HIV in the coming decades. Thus, the purpose of this article is to inform healthcare providers and researchers about the cognitive outcomes associated with HIV, diabetes, and aging independently within the context of cognitive reserve, and then to examine the potential synergistic effects of these conditions in individuals living with all three (Figure 1). This article also incorporates potential intervention strategies to protect and possibly improve cognitive functioning, or at the very least mitigate cognitive loss, in this population.

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Is There a Relationship between Mean Blood Glucose and Glycated Hemoglobin?

Cited by 84 publications

References 117 publications

Spironolactone and glucose metabolism, a systematic review and meta-analysis of randomized controlled trials

Spironolactone and glucose metabolism, a systematic review and meta-analysis of randomized controlled trials

Serum Fructosamine and Glycosylated Hemoglobin in Monitoring the Glycemic Control in Gestational Diabetes Mellitus

The Synergistic Effects of HIV, Diabetes, and Aging on Cognition

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