Is there an association between functional bladder outlet obstruction and Down's syndrome?

Hicks, James; Carson, C.; Malone, P.S.

doi:10.1016/j.jpurol.2007.02.003

Cited by 17 publications

(14 citation statements)

References 9 publications

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“…People with ID take more time of continence training. Not all people will become continent and if so functional bladder outlet obstruction is an issue (Hicks et al. 2007).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Unnoticed post‐void residual urine volume in people with moderate to severe intellectual disabilities: prevalence and risk factors

Waal

Tinselboer

Evenhuis

et al. 2009

J intellect Disabil Res

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“…People with ID take more time of continence training. Not all people will become continent and if so functional bladder outlet obstruction is an issue (Hicks et al. 2007).…”

Section: Introductionmentioning

confidence: 99%

“…People with ID take more time of continence training. Not all people will become continent and if so functional bladder outlet obstruction is an issue (Hicks et al 2007). Also the time spending on urinating is for some too long to fulfill, especially when it takes more time when aging.…”

Section: Introductionmentioning

confidence: 99%

Unnoticed post‐void residual urine volume in people with moderate to severe intellectual disabilities: prevalence and risk factors

Waal

Tinselboer

Evenhuis

et al. 2009

J intellect Disabil Res

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“…Non neurogenic-neurogenic syndrome in association with trisomy 21 was first identified by Handel et al who reviewed 26 children with DS (all boys) and found higher incidence of NNB compare to other urological abnormalities in DS (Handel et al, 2003). Hicks et al reported the first women with NNB associated with DS and also found higher incidence of NNB cases in trisomy 21 (Hicks et al, 2007).…”

Section: Historical Notementioning

confidence: 99%

“…Among 26 patients with DS who were reviewed, 4 (15.4%) was reported to have NNB (Handel et al, 2003). Hicks et al also found higher incidence of NNB cases in DS (Hicks et al, 2007). 23 Nonneurogenic neurogenic bladder has been reported not only in infant and children but also in adult patients (Handel et al, 2003;Hicks et al, 2007;Jayanthi et al, 1997;Kai et al, 2007).…”

Section: Epidemiologymentioning

confidence: 99%

Dysfunctional Voiding of Non-Neurogenic Neurogenic Bladder: A Urological Disorder Associated with Down Syndrome

Seki¹,

Shahab²

2011

Genetics and Etiology of Down Syndrome

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“…LUTS can be seen in up to 77% of these children. 6 In addition, incontinence rates between 46% and 73% are present in children with DS. These rates are higher in children with low IQ and LUTS.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of lower urinary tract symptoms in children with Down syndrome: A prospective, case‐controlled cohort study

Kızılay

İrer

Kızılay

et al. 2020

Neurourology and Urodynamics

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Aims: In children with Down syndrome (DS) which causes cognitive impairment and intellectual disability (ID), dysfunctional voiding is proposed to be more common than in the normal population. In this study, we aimed to compare the voiding symptoms of DS children with a control group by validated questionnaires.Methods: Thirty-seven DS children without any previous urological complaints and 59 non-DS healthy children as control group was included in the study.Overactive bladder symptoms and dysfunctional voiding were evaluated with validated Overactive Bladder Questionnaire (OAB-V8) and Dysfunctional Voiding Symptom Score (DVSS) questionnaire, respectively. Data were arranged, descriptive and comparative statistical analysis were performed. Results: Demographic data of the two groups were similar except age of completing toilet training being higher in DS group. Total OAB-V8 and DVSS scores were significantly higher in the DS group. The mean scores of questions regarding voiding frequency, urgency and urgency incontinence in OAB-V8 were significantly higher in the DS group. The mean daytime incontinence, urgency, urgency incontinence, and quality of life scores in the DVSS were also significantly higher in the DS group.Conclusions: DS children have more frequent dysfunctional voiding than the normal population. ID of these children may prevent the expression of these symptoms. Awareness and early detection of these symptoms are crucial to prevent devastating complications such as renal failure. Therefore, validated questionnaires are simple, useful, and noninvasive methods. K E Y W O R D S Down syndrome, dysfunctional voiding, dysfunctional voiding symptom score, overactive bladder questionnaire, urinary incontinence Abbreviations: DS, Down syndrome; DVSS, Dysfunctional Voiding Symptom Score; ID, intellectual disability; IQ, intelligence quotient; LUTS, lower urinary tract symptoms; OAB-V8, Overactive Bladder Questionnaire; QoL, quality of life.

show abstract

Is there an association between functional bladder outlet obstruction and Down's syndrome?

Cited by 17 publications

References 9 publications

Unnoticed post‐void residual urine volume in people with moderate to severe intellectual disabilities: prevalence and risk factors

Unnoticed post‐void residual urine volume in people with moderate to severe intellectual disabilities: prevalence and risk factors

Dysfunctional Voiding of Non-Neurogenic Neurogenic Bladder: A Urological Disorder Associated with Down Syndrome

Evaluation of lower urinary tract symptoms in children with Down syndrome: A prospective, case‐controlled cohort study

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