Is there any Correlation between the Results of Skin-Prick Test and the Severity of Symptoms in Allergic Rhinitis?

Background Skin prick test (SPT) is the most common diagnostic procedure that is performed considering the history of aeroallergen sensitivity among patients. Moreover, it is important to identify the diagnostic and therapeutic benefits of allergen’s number in skin prick testing in both adults and children. Objective The present study aims to detect the minimum number of allergens used in SPT to identify 95% of sensitized patients in both pediatric and adult age groups in Jordan. Patients and Methods Retrospective analysis of a 20 allergen extracts SPT results for 2253 patients (aged 8 and above) was conducted to assess the minimum number of allergen extracts needed to identify 95% of the sensitized patients in both adults and children. Results The results showed that 50.9% of the pediatric group was sensitized to at least one aeroallergen extract in comparison to 48.3% of the adult group. Only 8 allergen extracts were necessary to identify 95% of the sensitized patients which are olive pollen, Dermatophagoides pteronyssinus , Salsola kali, 4 cereals, Wall pellitory, Dermatophagoides farinae , Cypress and mugwort. Same number was needed in children but with the replacement of mugwort with alternaria to achieve a similar result. Conclusion The study concluded that only 8 allergen extracts were needed for detecting 95% of sensitized patients (both pediatrics and adults) in SPT. The authors proposed a two-stage screening: stage 1 includes the minimum number of allergen extracts to detect 95% of sensitized patients and stage 2 for the patients who tested negative in stage 1 which will include a broader allergen extracts panel excluding those which were already tested in stage 1.

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“…Regardless of these drawbacks, it remains the standard method for diagnosis of IgE-mediated allergies. 10 , 13 , 19 …”

Section: Discussionmentioning

confidence: 99%

<p>Minimizing the Number of Aeroallergen Extracts in Skin Prick Test in IgE-Mediated Allergic Disorders in Both Adults and Children in Jordan</p>

Khreesha

Ghunaim

Ramzown

et al. 2020

JAA

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“…Skin prick testing 12, 13 , was used to assess allergic status to a battery of 9 allergens: house dust mite ( Dermatophagoides pteronyssinus (Der P 1)), North American dust mite ( Dermatophagoides farinae ), ragweed, mold mix, weed mix, tree mix, grass mix, cat dander, and sagebrush. All participants met skin prick test (SPT) criteria for sensitivity to Der P 1 due to research objectives for the primary study 11 .…”

Section: Methodsmentioning

confidence: 99%

“…In a study of individuals with AR, anxiety enhanced the impact of stress on allergen-induced histamine release in response to skin prick tests 11 . Skin prick testing is a major diagnostic tool in the clinic and can serve to confirm whether patient symptomatology is due to allergy 12, 13 . The findings from our original study were based on an examination of wheal responses to antigens for which individuals met diagnostic criteria for allergy, that is, they reported a symptom history consistent with allergy and also showed clinically positive skin prick test (SPT) responses at baseline.…”

Section: Introductionmentioning

confidence: 99%

Stress and anxiety effects on positive skin test responses in young adults with allergic rhinitis

Heffner

Kiecolt‐Glaser

Glaser

et al. 2014

Annals of Allergy, Asthma & Immunology

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“…VAS can be used in all age groups including preschool children (guardian evaluation) (90) and the elderly (91). Furthermore, it can be used in a wide variety of languages (81,(91)(92)(93)(94)(95)(96)(97). VAS levels vary with the ARIA classification in many languages (76, 79, …”

Section: Measures Of Allergic Rhinitis Controlmentioning

confidence: 99%

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

Bousquet

Schünemann

Fonseca

et al. 2015

Allergy

177

172

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Is there any Correlation between the Results of Skin-Prick Test and the Severity of Symptoms in Allergic Rhinitis?

Abstract: ABSTRACT

Cited by 20 publications

References 20 publications

<p>Minimizing the Number of Aeroallergen Extracts in Skin Prick Test in IgE-Mediated Allergic Disorders in Both Adults and Children in Jordan</p>

<p>Minimizing the Number of Aeroallergen Extracts in Skin Prick Test in IgE-Mediated Allergic Disorders in Both Adults and Children in Jordan</p>

Stress and anxiety effects on positive skin test responses in young adults with allergic rhinitis

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

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