“…In this issue of Advances in Interventional Cardiology , 2 case reports describe successful application of manual thrombectomy beyond the scope of routine STEMI management (a patient with breast cancer and paraneoplastic syndrome, who suffered non-ST-segment myocardial infarction and a patient with bacterial endocarditis of the aortic valve and anterior STEMI caused by embolization of thrombotic material into the left anterior descending (LAD) coronary artery) [ 5 , 6 ].…”