Is warfarin sodium contraindicated in the lactating mother?

McKenna, Rajalaxmi; Cole, Edmond R.; Vasan, Ushanalini

doi:10.1016/s0022-3476(83)80378-3

Cited by 139 publications

(39 citation statements)

References 3 publications

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“…There have been two convincing reports demonstrating that warfarin is not detected in breast milk and does not induce an anticoagulant effect in the breast-fed infant when nursing mothers consume the drug. 98,99 Acenocoumarol, which is commonly used in Europe, has similar properties (Tables S4, S5). 100,101 Therefore, the use of warfarin and acenocoumarol in women who require postpartum anticoagulant therapy is safe.…”

Section: Use Of Vitamin K Antagonists In Breast-feeding Womenmentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,310

591

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Summary of RecommendationsNote on Shaded Text: Throughout this guideline, shading is used within the summary of recommendations sections to indicate recommendations that are newly added or have been changed since the publication of Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Recommendations that remain unchanged are not shaded. Abbreviations: APLA 5 antiphospholipid antibody; aPPT 5 activated partial thromboplastin time; HIT 5 heparin-induced thrombocytopenia; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; NNT 5 number needed to treat; PE 5 pulmonary embolism; RR 5 risk ratio; UFH 5 unfractionated heparin

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Section: Use Of Vitamin K Antagonists In Breast-feeding Womenmentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,310

591

View full text Add to dashboard Cite

show abstract

“…There is convincing evidence that, when administered to a nursing mother, warfarin does not induce an anticoagulant effect in the breast-fed infant. 180,181 …”

Section: Anticoagulation During Pregnancymentioning

confidence: 99%

American Heart Association/American College of Cardiology Foundation Guide to Warfarin Therapy

Hirsh¹,

Fuster²,

Ansell³

et al. 2003

Circulation

711

542

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“…15 There were 2 convincing reports that warfarin does not induce an anticoagulant effect in the breast-fed infant when the drug is administered to a nursing mother, 16,17 and so it can also be given to women requiring anticoagulant therapy postpartum who wish to breast feed.…”

Section: Discussionmentioning

confidence: 99%