Ischaemic heart disease in the elderly.

Kennedy, Robert; Andrews, Gary R.; Caird, F. I.

doi:10.1136/hrt.39.10.1121

Cited by 50 publications

(13 citation statements)

References 21 publications

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“…Silent ischemic heart dis ease, a potentially arrhythmogenic condi tion, has been recognized both clinically and pathologically in a sizable proportion of ap parently healthy elderly individuals [4][5][6], In this study, we considered 'healthy' those el derly subjects in whom clinical history, phys ical examination and baseline ECG did not show any abnormality. Our objective was to record the cardiac rate and rhythm modifi cations that appear in healthy elderly people during their normal activity, therefore, we did not request them to change their habits, in contrast to the investigation of Hinkle et al [7], where they encouraged an increase in cardiac work over normal for 6 h.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Rate and Hyperkinetic Rhythm Disorders in Healthy Elderly Subjects: Evaluation by Ambulatory Electrocardiographic Monitoring

Ribera

Cruz²,

Zamorano³

et al. 1989

Gerontology

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We performed 24-hour ambulatory electrocardiographic (Holter) examinations in 50 retired hospital workers (30 men, 20 women), aged 58–85 years (mean age ± SD: 65.9 ± 4.6 years), with a normal clinical history, physical examination and baseline ECG. There was a significant difference between daytime and nocturnal mean heart rates (79.2 ± 8.4 vs. 65.3 ± 7.8 beats per minute), and between maximal (122.4 ± 15.6 vs. 99.9 ± 13.7) and minimal (57.9 ± 10.8 vs. 51.3 ± 8.0) diurnal and nocturnal heart rates. 92% of the subjects were shown to have supraventricular extrasystoles (SVE) in the 24 h recording, with 16% having more than 100 SVE/h. 68% had ventricular extrasystoles (VE), but only 6% had more than 100 VE/h. SVE were mainly diurnal, and VE were equally distributed between day and night. No other rhythm disturbances were found in this group of healthy elderly individuals.

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Section: Discussionmentioning

confidence: 99%

Cardiac Rate and Hyperkinetic Rhythm Disorders in Healthy Elderly Subjects: Evaluation by Ambulatory Electrocardiographic Monitoring

Ribera

Cruz²,

Zamorano³

et al. 1989

Gerontology

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“…13 The paradoxical possibility that a high TC is associated with longer, rather than shorter, survival in subjects in the 7th decade of life has been suggested in 1990 by the results of the EWPHE, 14 where TC measured at randomisation was independently and inversely correlated with total mortality.…”

Section: Serum Total Cholesterol (Tc)mentioning

confidence: 99%

Cardiovascular risk factors in the elderly

Casíglia

Palatini

1998

J Hum Hypertens

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Although a number of risk factors for cardiovascular morbidity and mortality have been identified in young and middle-aged adults, their prevalence and importance are less known in the elderly. Elderly people have a risk profile different from that of younger subjects, but representative data on risk factors for cardiovascular disease in the elderly are difficult to find in the literature. Some typical 'major' risk factors, like blood pressure (BP), total cholesterol or left ventricular hypertrophy, do

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“…They concluded, however, that there is no direct evidence of the desirability of persuading elderly smokers to stop smoking. Kitchin et al (41) and Kennedy et al (28) found smoking to be a significant risk factor in the aged.…”

Section: Late Prognosis For Acute Myocardial Infarction In the Agedmentioning

confidence: 99%

“…Kennedy et al (28) found that not only was there no association between obesity and ischemic heart disease in the elderly, but that ischemic heart disease was more common among thinner subjects. These authors concluded that either obese persons do not survive to old age, or obesity is less of a risk factor in the aged.…”

Section: Late Prognosis For Acute Myocardial Infarction In the Agedmentioning

confidence: 99%

Ischemic and Hypertensive Heart Disease in the Aged: Prognostic and Therapeutic Factors†

Rodstein

1980

J American Geriatrics Society

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The prognostic significance of risk factors for ischemic and hypertensive heart disease in the aged differs in many respects from that in younger persons. In old age, most risk factors for ischemic heart disease such as an elevated level of total serum cholesterol, cigarette smoking, obesity, Type A personality and abnormal glucose tolerance have a less adverse effect on morbidity and mortality from ischemic heart disease, while an elevated level of high density lipoprotein, and moderation in the use of alcohol each have a favorable effect. A high level of low-density lipoprotein cholesterol exerts an adverse effect. Both systolic and diastolic hypertension have an adverse influence on morbidity and mortality from ischemic and hypertensive heart disease, as does the electrocardiogrpahic pattern of left ventricular strain. Long-term controlled studies are needed to determine the effects on mortality and morbidity of the modification of risk factors by means of drugs, diet, and change of lifestyle. Such studies are necessary if we are to determine whether hoped-for favorable changes are offset by potential side effects on physical and mental health.

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Ischaemic heart disease in the elderly.

Cited by 50 publications

References 21 publications

Cardiac Rate and Hyperkinetic Rhythm Disorders in Healthy Elderly Subjects: Evaluation by Ambulatory Electrocardiographic Monitoring

Cardiac Rate and Hyperkinetic Rhythm Disorders in Healthy Elderly Subjects: Evaluation by Ambulatory Electrocardiographic Monitoring

Cardiovascular risk factors in the elderly

Ischemic and Hypertensive Heart Disease in the Aged: Prognostic and Therapeutic Factors†

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