“…There are many underlying factors that can contribute to the development of tongue necrosis (Table 1 ). 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 Giant cell arteritis (GCA), ANCA (Anti‐Neutrophil Cytoplasmic Antibody)‐associated vasculitis and other vasculitides have been previously described as underlying systemic causes of tongue necrosis. 1 , 2 , 3 , 4 Other potential causes include infection (particularly tuberculosis and syphilis), malignancy, radiation therapy, use of vasoconstricting medications and systemic hypoperfusion such as in the setting of shock.…”