Ischemic Colitis

Hernández, Luis; Fitzgerald, James

doi:10.1055/s-0035-1549099

Cited by 48 publications

(36 citation statements)

References 28 publications

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“…The marginal artery of Drummond protects the colon from ischemia by forming a system of arcades connecting the major arteries and the meandering mesenteric artery (arc of Riolan) ( 1 ). Anatomically, two areas of the colon are considered more vulnerable for ischemia: The first vulnerable area is the splenic flexure (Griffith’s point).…”

Section: Etiology and Anatomic Considerationsmentioning

confidence: 99%

“…The classic symptomatology of IC consists of abdominal pain, hematochezia, and leucocytosis in an elderly patient ( 1 ). These symptoms vary considerably and depend mainly on the degree of the ischemia and the length and the thickness of the colon that is affected.…”

Section: Clinical Presentationmentioning

confidence: 99%

“…It was also higher for open repair (1.9%) than endovascular repair (0.5%). Regardless of the surgical approach, IC was associated with increased morbidity and a two- to fourfold increase in mortality ( 1 , 30 ).…”

Section: Risk Factorsmentioning

confidence: 99%

“…It is an insult to the colonic wall resulting from diminished blood flow. This can range from superficial injury of the mucosa and submucosal layer to full thickness necrosis of the colonic wall ( 1 ). Most attacks are transient and resolve spontaneously, whereas others may result to gangrene and necrosis of the colon with resultant perforation and feculent peritonitis.…”

Section: Introductionmentioning

confidence: 99%

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Advents in the Diagnosis and Management of Ischemic Colitis

Misiakos

Tsapralis²,

Karatzas

et al. 2017

Front. Surg.

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BackgroundIschemic colitis (IC) is a common type of ischemic insult, resulting from decreased arterial blood flow to the colon. This disease can be caused from either atherosclerotic occlusive vascular disease or non-occlusive disease. The aim of this study is to present the diagnostic methodology and management of this severe disease based on current literature.MethodsA literature search has been done including articles referring to modern diagnosis and management of IC.ResultsIC is usually a transient disease, but it can also cause gangrene of the colon, requiring emergency surgical exploration. Diagnosis is troublesome and is based on imaging examinations, mainly computerized tomography, which in association with colonoscopy can delineate the distribution pattern and severity of disease.ConclusionThe majority of patients with mild disease have usually complete clinical recovery within a short period. The severe forms of the disease carry high morbidity and mortality rates and prompt surgical intervention is the only way to improve the associated severe prognosis.

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Section: Etiology and Anatomic Considerationsmentioning

confidence: 99%

Section: Clinical Presentationmentioning

confidence: 99%

Section: Risk Factorsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Advents in the Diagnosis and Management of Ischemic Colitis

Misiakos

Tsapralis²,

Karatzas

et al. 2017

Front. Surg.

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“…Ischemic colitis (IC), also known as colon ischemia, is the most common type of intestinal ischemia caused by damage to the colonic wall resulting from reduced blood flow [1]. This can vary from superficial injury of the mucosa and submucosal layer to full-thickness necrosis of the colonic wall [2]. Most instances are transient and resolve spontaneously with hospitalization and expectant management.…”

Section: Introductionmentioning

confidence: 99%

Fulminant Ischemic Pancolitis: A Severe Variant of Ischemic Colitis

Gupta¹,

Vazquez²,

Burgos³

et al. 2020

Cureus

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We present the case of a 75-year-old female with abdominal pain and a sudden change in mental status. She progressed rapidly with manifestations of acidosis without episodes of bloody bowel movements or diarrhea. The patient underwent emergent exploratory laparotomy, and a diagnosis of fulminant ischemic pancolitis was made with visual confirmation of infarcted colon from cecum to proximal rectum leading to subtotal colectomy and ileostomy. Postoperatively, the patient showed improved acidosis and mental status; unfortunately, over the subsequent days, the patient declined and was transferred to hospice and palliative care.

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Surgical prevalence and outcomes in ischemic colitis: A systematic review and meta‐analysis

Qian,

Bruinsma,

Mac Curtain

et al. 2024

World j. surg.

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Background/AimThis study reviews the literature to examine the proportion of patients requiring surgical management in ischemic colitis (IC) and identify surgical outcomes.MethodA systematic review of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials was conducted in accordance with the latest Preferred Reporting Items for Systematic Reviews and Meta‐analyses (PRISMA) statement. English language studies and adult patients were included. Studies with fewer than 10 patients, and IC post aortic or cardiac surgery was excluded. We present our systematic review and meta‐analysis with pooled proportions of right sided IC distribution and prevalence of surgical treatment.Results23 studies with a total of 12,844 patients were included in the systematic review, with 19 studies and 12,420 patients included in the meta‐analysis. Four studies were excluded from the meta‐analysis due to only including specific cohorts of patients—two with cocaine induced colitis, one with phlebosclerotic colitis, and one with IC associated with acute myocardial infarction. The pooled proportion of right sided IC distribution was 15% (CI 14%–17%, p < 0.001), whilst the pooled proportion of surgical management of IC was 15% (CI 13%–16% p < 0.001).ConclusionPrevalence of surgical management of IC is rare. Right sided IC is associated with higher mortality and higher rates of surgical management. Reporting of surgical outcomes is scant.

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Ischemic Colitis

Cited by 48 publications

References 28 publications

Advents in the Diagnosis and Management of Ischemic Colitis

Advents in the Diagnosis and Management of Ischemic Colitis

Fulminant Ischemic Pancolitis: A Severe Variant of Ischemic Colitis

Surgical prevalence and outcomes in ischemic colitis: A systematic review and meta‐analysis

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