Ischemic Colitis

Johnson, Dirk C.; Davis, Kimberly A.

doi:10.1007/978-3-319-96286-3_26

Cited by 1 publication

(1 citation statement)

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“…Colonic ischemia is the most frequent form of intestinal ischemia with an annual incidence of approximately 1.6 cases per 100,000 individuals, rising to 18 cases per 100,000 among hospitalized patients. 1 Although older, hospitalized patients with atherosclerotic risk factors are typically affected, it is rare in otherwise healthy young people. Young women may experience ischemic colitis (IC) because of hormonal therapy's prothrombotic effects.…”

Section: Introductionmentioning

confidence: 99%

Progesterone-Only Contraceptive-Induced Ischemic Colitis

Rajamanuri,

Garg,

Siddiqui

et al. 2024

ACG Case Rep J

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Ischemic colitis (IC) occurs when there is a temporary lack of adequate blood supply to the intestines, particularly in vulnerable areas such as the splenic flexure and sigmoid colon, which lack sufficient collateral blood vessels. Although primarily seen in older individuals with atherosclerotic risk factors, IC can also be triggered by hormonal contraceptives in young women. Although estrogen-containing oral contraceptives are known to increase thromboembolic risk, the impact of progesterone is not well understood. We report a unique case of biopsy-confirmed IC in a previously healthy 30-year-old woman who presented with abdominal pain and bloody diarrhea 2 months after initiation of progesterone-only oral contraceptive. This occurrence, although rare, underscores the need for further research on the impact of progesterone on coagulation, especially concerning mesenteric arteries.

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Section: Introductionmentioning

confidence: 99%