Ischemic priapism in South-East Nigeria: Presentation, management challenges, and aftermath issues

Ugwumba, FO; Ekwedigwe, HC; Echetabu, KN; Okoh, AD; Nnabugwu, Ikenna I; Ugwuidu, E.S.I.

doi:10.4103/1119-3077.175968

Cited by 21 publications

(23 citation statements)

References 22 publications

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“…In the group of the patients older than 18 years of age who were analyzed with EHS and SSL, those with a history of priapism had significantly worse erections: EHS scored 2 [1][2][3] in comparison to individuals with PE (EHS=4 [3][4]; p=0.01) (Figure 3). Also, the patients who had priapism were less satisfied with their sexual life than the individuals with PE (SSL=2 [1][2]; versus 3 [3-5]; p=0.02) (Figure 4).…”

Section: ❚ Resultsmentioning

confidence: 99%

“…A projeção estatística foi de que 71,1% desses sujeitos teriam pelo menos um episódio de priapismo ao longo da vida. Pacientes adultos com episódios de priapismo (10/23) apresentaram função erétil significativamente pior Escala de Rigidez de Ereção de 2 [1][2][3]; p=0,01 e estavam menos satisfeitos com a vida sexual 3 [3][4][5]; p=0,02. Conclusão: O priapismo manifesta-se desde a infância, e episódios graves estão associados a dano cavernoso, prejuízo na qualidade da ereção e menor satisfação sexual.…”

Section: ❚ Resumounclassified

“…(1,2) This disease is recognized by the World Health Organization (WHO) as a serious global public health problem, with great impact on the morbidity and mortality of the affected population. (3) It affects mainly Afrodescendants, and its pathophysiology is related to the occurrence of vaso-occlusive episodes, in small vessels, leading to the signs and symptoms of the disease. (2) The estimated prevalence of SCD in Brazil is 25,000 to 50,000 individuals, with the incidence of 1 case to every 650 live births in Northeastern regions and 1 to every 1,300 in the South region of the country.…”

Section: ❚ Resumomentioning

confidence: 99%

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Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

Alvaia¹,

Maia²,

Nelli³

et al. 2020

Einstein (São Paulo)

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Objective: To evaluate epidemiological aspects of priapism in patients with sickle cell disease, and these aspects impact on adult sexual function. Methods: This was a cross-sectional study including individuals with sickle cell disease who were evaluated at a reference center for sickle cell. Participants completed a structured questionnaire about their sociodemographic characteristics and priapism events. Sexual function was assessed using validated two instruments, the Erection Hardness Score and one about the sex life satisfaction. Results: Sixty-four individuals with median aged of 12 (7 to 28) years were interviewed. The prevalence of priapism was 35.9% (23/64). The earliest priapism episode occurred at 2 years of age and the latest at 42 years. The statistical projection was that 71.1% of individuals of the study would have at least one episode of priapism throughout life. Patients with episodes of priapism (10/23) had significantly worse erectile function Erection Hardness Score of 2 [1-3]; p=0.01 and were less satisfied with sexual life 3 [3-5]; p=0.02. Conclusion: Priapism is usually present in childhood, and severe episodes are associated with cavernous damage, impairment in the quality of the erection, and lower sexual satisfaction.

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Section: ❚ Resultsmentioning

confidence: 99%

Section: ❚ Resumounclassified

Section: ❚ Resumomentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

Alvaia¹,

Maia²,

Nelli³

et al. 2020

Einstein (São Paulo)

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“…According to Ogwumba et al (2015), in more than half of the cases of SCD patients who previously suffered from stuttering priapism, low-flow priapism presents itself subsequently. In a bid to determine the etiology, presentation, management, and outcomes of ischemic priapism, Ogwumba et al (2015) studied 27 patients who were undergoing ischemic priapism management in three hospitals in South East Nigeria between January 2000 and December 2010. Clinical data such as clinical features, interval and onset of presentation, and type of priapism were retrieved.…”

Section: Low Flow (Ischemic) Priapism Ischemic Priapism Does Not Havmentioning

confidence: 99%

“…Eight of the 15 patients had SCD and had previously suffered from stuttering priapism before advancing to ischemic priapism. Four had unidentified causes (Ogwumba et al, 2015). Six had taken herbal medications before the presentation of medical attention.…”

Section: Low Flow (Ischemic) Priapism Ischemic Priapism Does Not Havmentioning

confidence: 99%

Priapism Among Male Adolescents with Sickle Cell Disease

Ocansey¹

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Management of acute sickle cell priapism in an African (Togo) pediatric department includes conservative measures and intracavernous epinephrine which is safe and efficacious

Guedenon

Fiawoo

Akolly

et al. 2022

eJHaem

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Priapism is a well-known urologic complication of sickle cell anemia. This study describes the results of a protocol for the treatment of acute priapism by intracavernous injection of epinephrine due to unavailability of etilefrine. A descriptive cross-sectional study of 18 cases of acute priapism in sickle cell patients treated in the pediatric department of the Sylvanus Olympio CHU from January 1 to December 31, 2020. The average age was 21.7 ± 7.7 years, the youngest patient was 8 and the oldest was 32 years old. Students represented 61.1% of the patients. The hemoglobin profiles were homozygous SS (n = 14) and double heterozygous SC (n = 4). Most of the crisis (83.3%) occurred at night. Most of the patients (66.7%) came to the hospital before the sixth hour of crisis, one patient came by the 48th hour. Walking was the most self-relief method tried by patients (67%). It was followed by a cold penile bath, attempted urination, body bath, and lastly lukewarm bath. Fourteen patients had a history of chronic intermittent priapism. The average pain intensity was 9.5 ± 0.9 with restlessness (33.3%) and crying (33.3%). Fifteen patients were treated upon admission with an intracavernosal injection of epinephrine, and three patients were first drained.Thirteen patients achieved remission immediately, while five patients required a second injection and only one had to be drained before remission. Tolerance was good.One patient had a borderline systolic blood pressure. One erectile weakness case was noticed and no cases of sexual impotence. Epinephrine by intracavernosal injection is an efficient treatment for acute priapism in sickle cell patients. Epinephrine, which has a good tolerance in pediatric and young adult patients, should be used in lieu of etilefrine due to its unavailability in areas where it is unavailable.

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Ischemic priapism in South-East Nigeria: Presentation, management challenges, and aftermath issues

Cited by 21 publications

References 22 publications

Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

Priapism Among Male Adolescents with Sickle Cell Disease

Management of acute sickle cell priapism in an African (Togo) pediatric department includes conservative measures and intracavernous epinephrine which is safe and efficacious

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