Isobaric bupivacaine and hyperbaric amethocaine for spinal analgesia

Tattersall, M. P.

doi:10.1111/j.1365-2044.1983.tb13928.x

Cited by 16 publications

(3 citation statements)

References 7 publications

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“…Our results with glucose-free bupivacaine are comparable to those obtained with isobaric amethocaine (Wildsmith et al, 1981). Another possible advantage of glucose-free solution is the ability to position patients with painful conditions such as fractured neck of femur with the painful side uppermost, and to be able to re-position them painlessly for operation within a few minutes (Tattersall, 1983).…”

Section: Discussionsupporting

confidence: 74%

Subarachnoid Blockade With Bupivacaine

Cummings

Bamber

Edström

et al. 1984

British Journal of Anaesthesia

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Subarachnoid anaesthesia was induced in 40 patients with 0.5% bupivacaine 3 ml with no glucose, 5% glucose or 8% glucose, or with hyperbaric cinchocaine . The injections were made in the lateral position and the patients turned supine immediately. The onset, extent and duration of sensory and motor blockade, the quality of anaesthesia, cardiovascular effects, and the frequency of side-effects were studied. The hyperbaric solutions produced a greater cephalad spread (T6-T7) than the glucose-free solution (T10-T11). Cinchocaine produced a longer duration of action at T10 and T12 than the hyperbaric bupivacaine solutions. No advantage was seen when 8% rather than 5% glucose was used. The glucose-free bupivacaine produced intense blockade of long duration and was suitable when a lower level of blockade was adequate for the proposed surgery.

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Section: Discussionsupporting

confidence: 74%

Subarachnoid Blockade With Bupivacaine

Cummings

Bamber

Edström

et al. 1984

British Journal of Anaesthesia

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“…However, results from studies on bupivacaine used for subarachnoid analgesia give some indication of possible effects. After a bolus injection of 0.5% bupivacaine 15-20 mg, blockade usually does not extend above T4 (Chambers, Edstrom and Scott, 1981;Kalso, Tuominen and Rosenberg, 1982;Tuominen, Kalso and Rosenberg, 1982;Russell, i983;Ryan, Pridie and Copeland, 1983;Sheskey et al, 1983;Tattersall, 1983). The block then regresses at about two segments per hour.…”

Section: Discussionmentioning

confidence: 99%

Continuous Extradural Infusion of 0.0625% or 0.125% Bupivacaine for Pain Relief in Primigravid Labour

Rees

Rosen

1985

British Journal of Anaesthesia

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The efficacy of an extradural infusion of 0.0625% or 0.125% bupivacaine was studied in 98 primigravid mothers in active labour. No special measures were taken to posture the mother (except to avoid aorto-caval compression). The study regimen included a control group (no infusion) receiving intermittent top-ups (0.25%. bupivacaine 8-10 ml), two groups receiving bupivacaine 6.25 mg h-1 infusion in different concentrations (0.0625% and 0.125%), a fourth group receiving 0.125% bupivacaine 12.5 mg h-1 infusion, and a fifth group receiving 0.125% bupivacaine 18.75 mg h-1 infusion. The optimum infusion rate was 0.125% bupivacaine 10 ml h-1, at which 69% of primigravid mothers required none or only one "top-up" of 0.25% bupivacaine 8-10 ml during a mean duration of 7.1 h labour. In the group who had no extradural infusion, only 32% of mothers managed with one or no top-up. The median interval between top-ups was increased from 145 min in the no infusion group to 245 min in those mothers receiving 0.125% bupivacaine 10 ml h-1 by infusion. Increasing the rate of infusion to 15 ml h-1 did not improve the results. Spread of local anaesthetic to higher levels was limited (less than T5) so that testing sensory loss at the T5-6 level at 2-hourly intervals should detect accidental spinal blockade resulting from inadvertent intrathecal infusion.

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“…Thus, hyperbaric tetracaine seems to have a profile similar to that of plain 0.5% bupivacaine, provided the doses in milligrams are comparable (56,92). Plain tetracaine has been shown to produce a longer-lasting sensory block than plain bupivacaine It has been reported that the degree of hypotension during spinal anaesthesia is less in patients given plain or hyperbaric bupivacaine as compared with hyperbaric tetracaine (70,93,94). However, when the degree of sympathetic block associated wirk haemodynamic changes was evaluated, the difference between bupivacaine and tetracaine solutions was insignificant at identical levels of sensory analgesia (82).…”

Section: Bupivacaine Vs Other Intrathecal Local Anaestheticsmentioning

confidence: 99%

Bupivacaine spinal anaesthesia

Tuominen

1991

Acta Anaesthesiol Scand

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Isobaric bupivacaine and hyperbaric amethocaine for spinal analgesia

Cited by 16 publications

References 7 publications

Subarachnoid Blockade With Bupivacaine

Subarachnoid Blockade With Bupivacaine

Continuous Extradural Infusion of 0.0625% or 0.125% Bupivacaine for Pain Relief in Primigravid Labour

Bupivacaine spinal anaesthesia

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