Isolated AA Amyloidosis of the Radial Nerve

Fuente, Teresa Pérez-de la; Fernández-Jara, Javier; Rodríguez-Urcelay, Pilar; Jiménez‐Heffernan, José A.; Juárez, Ángel

doi:10.1177/1558944717702469

Cited by 4 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2,26 Furthermore, amyloid-ApoAI amyloidosis, 28 amyloid-gelsolin amyloidosis, 6 and amyloid-β2 microglobulin amyloidosis 30 also cause autonomic neuropathy due to amyloid deposition in the PNS. On the other hand, AA deposition in PNS is extremely rare in humans, although idiopathic cases of AA deposition in the radial nerve 21 and vestibulocochlear nerve 29 have been reported. Why AA amyloidosis rarely causes peripheral nervous amyloid deposition has not been clarified.…”

Section: Discussionmentioning

confidence: 99%

AA Amyloid Deposition in the Central and Peripheral Nervous Systems in Flamingos

et al. 2020

View full text Add to dashboard Cite

AA amyloidosis is characterized by amyloid deposition in systemic organs, but amyloid deposition in the central nervous system (CNS) or peripheral nervous system (PNS) is rare. In this study, AA amyloidosis was observed in 31 of 48 flamingos that died at a Japanese zoo. Almost all cases developed AA amyloidosis secondary to inflammatory diseases such as enteritis. Affected flamingos had AA amyloid deposition around blood vessels in periventricular white matter of the brain and in peripheral nerves. In addition, cerebral Aβ amyloidosis was observed in one of the 31 cases with AA amyloidosis. In conclusion, flamingos in the zoo commonly developed systemic amyloidosis with frequent amyloid deposition in the CNS and PNS, which seems to be a unique distribution in this avian species. Comparative pathological analyses in flamingos may help elucidate the pathogenesis of amyloid neuropathy.

show abstract

Section: Discussionmentioning

confidence: 99%

AA Amyloid Deposition in the Central and Peripheral Nervous Systems in Flamingos

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Nevertheless, there are few case reports of upper limb mononeuropathy and autonomic neuropathy in the literature that are thought to develop due to AA amyloidosis. [3][4][5][6] A study examining the parameters of heart rate variability in severe and complicated FMF patients with amyloidosis revealed a significant difference compared to healthy controls. 7 In this study, we aimed to investigate the frequency of peripheral nerve and autonomic nerve involvement in adult FMF patients.…”

mentioning

confidence: 99%

Evaluation of peripheral nerve involvements in patients with familial Mediterranean fever

Karabacak,

İnan,

Şen

2023

Arch Rheumatol

View full text Add to dashboard Cite

Objectives: The aim of this study was to evaluate possible peripheral and autonomic nerve involvement in familial Mediterranean fever (FMF) patients with nerve conduction studies, sympathetic skin response (SSR) and RR interval variability (RRIV). Patients and methods: The comparative case series was conducted with 76 participants between November 2017 and December 2018. Forty-six FMF patients, [12 with amyloidosis (5 males, 7 females; mean age: 44.7±13.9 years) and 34 without amyloidosis (14 males, 20 females; mean age: 35.9±8.7 years)], and 30 healthy volunteers (11 males, 19 females; mean age: 38.4±10 years) were included in this study. Nerve conduction parameters, SSR latency and amplitude from palmar and plantar responses, and RRIV at rest and deep breathing were studied in all the subjects. Neuropathic symptoms of the patient group were evaluated using the survey of autonomic symptoms scale and the neuropathy disability score. Results: Nerve conduction studies of the patient group revealed polyneuropathy in seven (15.21%) patients and carpal tunnel syndrome in six (13.04%) patients. The mean amplitudes of SSR measured from the soles were significantly lower than the control group (p=0.041). The mean values of RRIV during rest and hyperventilation were lower in the patient group compared to the control group, but no statistically significant difference was found (p=0.484, p=0.341). Conclusion: We detected that the prevalence of carpal tunnel syndrome in our patient population (13.04%) was higher than in the general population. Most of the changes in the range of parameters of SSR and RRIV determined in the patient group did not reach statistical significance, suggesting subclinical dysautonomia in FMF patients.

show abstract

Amyloidosis

Raibagkar¹,

Venna²

2019

Neurorheumatology

View full text Add to dashboard Cite

Isolated AA Amyloidosis of the Radial Nerve

Abstract: Isolated radial nerve palsy due to nerve damage by amyloidosis has been reported before, but not in AA or secondary amyloidosis.

Cited by 4 publications

References 20 publications

AA Amyloid Deposition in the Central and Peripheral Nervous Systems in Flamingos

AA Amyloid Deposition in the Central and Peripheral Nervous Systems in Flamingos

Evaluation of peripheral nerve involvements in patients with familial Mediterranean fever

Amyloidosis

Contact Info

Product

Resources

About