2015
DOI: 10.2169/internalmedicine.54.4233
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Isolated Atrial Septal Defect Complicated by Tricuspid Valve Infective Endocarditis

Abstract: Infective endocarditis (IE) associated with atrial septal defect (ASD) is extremely rare. However, tricuspid regurgitation (TR) secondary to right ventricular overload is a potential cause of IE, and once it occurs, the development of a paradoxical embolism may lead to fatal complications. We herein report the case of a 50-year-old woman who was admitted due to a persistent fever resistant to antibiotics. Echocardiography showed secundum ASD, moderate TR and a mobile vegetation measuring 15×10 mm attached to t… Show more

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Cited by 2 publications
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“…Due to the slow shunt speed, the risk of IE from ASD was negligible, and it did not predispose the patient to IE. Therefore, IE associated with ASD is extremely rare, and only a few previous reports exist in the literature [23,24]. For this reason, we initially ignored the possibility of IE in the present case.…”
Section: Discussionmentioning
confidence: 95%
“…Due to the slow shunt speed, the risk of IE from ASD was negligible, and it did not predispose the patient to IE. Therefore, IE associated with ASD is extremely rare, and only a few previous reports exist in the literature [23,24]. For this reason, we initially ignored the possibility of IE in the present case.…”
Section: Discussionmentioning
confidence: 95%
“…○ Endocarditis in the presence of atrial septal defects is extremely rare due to the slow velocity of the shunt flow, and only few reported cases exist in the literature. An explanation of such occurrence could be related to the development of tricuspid regurgitation secondary to right ventricular volume overload which increases the risk of TV involvement [17].…”
Section: Risk Factorsmentioning
confidence: 99%