Isolated intracranial Rosai?-?Dorfman disease mimicking meningioma in a child

Griffiths, Stewart; Tang, Weijun; Parameswaran, Rajeev; Kelsey, Anna; West, Charles

doi:10.1080/02688690410001732788

Cited by 45 publications

(33 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Surgical resection has been found to be most effective [2,6,7]. However, in our case the lesion could not be resected completely owing to extensive involvement.…”

Section: Discussionmentioning

confidence: 53%

See 1 more Smart Citation

Isolated intracranial Rosai-Dorfman disease mimicking meningioma in a child: a case report and review of the literature

Gupta

Bagdi²,

Sunitha³

et al. 2011

BJR

View full text Add to dashboard Cite

ABSTRACT. We report the first case of extensive involvement of isolated intracranial Rosai-Dorfman's disease (RDD) in a child. Our case is unique because it presents with involvement of the middle cranial fossa, cavernous sinus, pituitary gland, orbit, ethmoid and sphenoid sinuses. Previous cases of intracranial RDD in children have reported separate involvement of cavernous sinus, suprasellar region, and frontal and petroclival regions. Involvement of the pituitary gland has so far not been reported. A 14-year-old male presented with a medical history of loss of vision, raised erythrocyte sedimentation rate (ESR), and abnormal prolactin and cortisol levels. Radiologically the diagnosis was meningioma. The histopathological diagnosis was RDD with emperipolesis and S-100 positivity. RDD is a histiocytic proliferation of unknown aetiology, which commonly affects lymph nodes. Uncommonly it involves the extranodal sites and rarely the central nervous system (CNS). 80 cases of RDD involving CNS have been reported in the literature, and only 5 were in children. Although the definitive diagnosis of RDD disease is based on the histopathology report, it should be included in the differentials of a lesion mimicking meningioma especially in children.

show abstract

“…Surgical resection has been found to be most effective [2,6,7]. However, in our case the lesion could not be resected completely owing to extensive involvement.…”

Section: Discussionmentioning

confidence: 53%

“…Although extranodal involvement is known to occur, isolated intracranial RDD is very rare. Out of 80 reported intracranial RDD cases, only 5 were in children [3][4][5][6][7][8].…”

mentioning

confidence: 99%

Isolated intracranial Rosai-Dorfman disease mimicking meningioma in a child: a case report and review of the literature

Gupta

Bagdi²,

Sunitha³

et al. 2011

BJR

View full text Add to dashboard Cite

show abstract

“…2 Pathogenesis has not been established; however, most theories implicate an aberrant response to an as-yet-uncharacterized antigen, possibly an infectious organism. 3 The imaging characteristics of SHML are not pathognomonic, but instead, prompt a differential diagnosis that includes lymphomatous, pseudolymphomatous, neoplastic, and infectious conditions.…”

mentioning

confidence: 99%

Isolated Intracranial Rosai-Dorfman Disease in a Child

Lungren¹,

Petrella²,

Cummings³

et al. 2009

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

“…Cuando afecta al SNC se presenta a edades más tardías (4ª-5ª décadas) que la forma clásica con afectación ganglionar cervical que suele afectar a niños y adolescentes 3,7 , aunque se han descrito casos en la infancia 5,10,30 . Hay autores que plantean la posibilidad de que se traten de dos entidades clínicas diferentes 28 , aunque histológicamente las lesiones sean idénticas.…”

Section: Epidemiologíaunclassified

Enfermedad de Rosai-Dorfman intracraneal: Presentación de un caso y revisión de la literatura

et al. 2011

View full text Add to dashboard Cite

255 Neurocirugía 2011; 22: 255-260 Resumen Introducción. La histiocitosis sinusal con linfadenopatías masivas (HSLM), también conocida como enfermedad de Rosai-Dorfman (ERD), es una histiocitosis idiopática que suele afectar a los ganglios linfáticos. Ocasionalmente puede afectar al SNC, siendo excepcional la afectación intracraneal sin lesiones ganglionares. En ausencia de signos radiológicos típicos, los pacientes afectos son generalmente intervenidos bajo la sospecha de un meningioma, obteniéndose el diagnóstico histológico tras el procedimiento quirúrgico. Es una entidad clínico-patológica poco conocida, existiendo controversia sobre su etiopatogenia, curso clínico y manejo terapéutico.Caso clínico. Presentamos el caso de un paciente de 40 años que debutó con dos crisis tónico-clónicas generalizadas y en la RM cerebral se objetivó una lesión extraaxial parieto-occipital izquierda con extensión hacia la fosa posterior, sin presentar lesiones a otros niveles. Se realizó una resección parcial de la lesión y la anatomía patológica fue informada como enfermedad de Rosai-Dorfman.Conclusiones. A pesar de su baja frecuencia, deberíamos incluir a la ERD en el diagnóstico diferencial de las lesiones nodulares durales, frente a otras más frecuentes como son los meningiomas. Debido a la inespecificidad de las pruebas complementarias su diagnóstico es eminentemente histológico. Se precisan más estudios para definir la mejor opción terapéutica.PALABRAS CLAVE. Enfermedad de Rosai-Dorfman. Histiocitosis sinusal con linfadenopatías masivas, Emperipolesis. Isolated intracranial Rosai-Dorfman disease: A case report and literature review SummaryIntroduction. Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease (RDD) is an idiopathic histiocytosis that usually affects the lymph nodes. Occasionally it may affect the CNS, being exceptional intracranial involvement without lymph node lesions. In the absence of typical radiological signs, affected patients are generally operated under the suspicion of a meningioma. The histological diagnosis is obtained after the surgical procedure. It is a clinicopathological entity not well known, controversy exists about its pathogenesis, clinical course and therapeutic management.Case report. We report the case of a 40-year-old male presented two generalized tonic-clonic seizures and brain MRI showed a left parieto-occipital extra-axial lesion extending into the posterior fossa, without presenting lesions at other levels. A partial resection of the lesion was performed and the histological findings were reported as Rosai-Dorfman disease.Conclusions. Despite its low frequency, the ERD should be included in the differential diagnosis of dural-based masses, compared to more common, such as meningiomas. Due to lack of specificity of additional studies its diagnosis is fundamentally histologic. More research is needed to define the best therapeutic option.KEY WORDS. Rosai-Dorfman disease. Sinus histiocytosis with massive lymphadenopathy. Emperipolesis. Introducció...

show abstract

Isolated intracranial Rosai?-?Dorfman disease mimicking meningioma in a child

Cited by 45 publications

References 13 publications

Isolated intracranial Rosai-Dorfman disease mimicking meningioma in a child: a case report and review of the literature

Isolated intracranial Rosai-Dorfman disease mimicking meningioma in a child: a case report and review of the literature

Isolated Intracranial Rosai-Dorfman Disease in a Child

Enfermedad de Rosai-Dorfman intracraneal: Presentación de un caso y revisión de la literatura

Contact Info

Product

Resources

About